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Found 14 clinical trials
Featured trial
A multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of AGB101 (low-dose levetiracetam, 220 mg, extended release tablet) on slowing progression of mild cognitive impairment due to Alzheimer's disease

A study for patients with mild cognitive impairment due to Alzheimer's disease with short memory loss.  

mild cognitive impairment
memantine
cognitive impairment
dementia
ginkgo biloba
  • 161 views
  • 08 Dec, 2020
  • 1 location
A Study to Investigate JNJ-40411813 in Combination With Levetiracetam in Epilepsy

with focal onset seizures who are receiving levetiracetam and up to 3 other anti-epileptic drugs (AEDs) (double-blind treatment period) and to evaluate the long-term efficacy and safety of adjunctive

  • 7 views
  • 02 Jun, 2022
  • 26 locations
R33: Levetiracetam in Early Psychosis

This is a 12-week study of levetiracetam added to a second generation antipsychotic in early psychosis patients who have been ill for less than 5 years and continue to experience psychotic

  • 0 views
  • 04 Jun, 2022
  • 1 location
Pharmacokinetic and Placental Transfer of Levetiracetam (EPICEINTE)

other hand. There is limited data on the pharmacokinetics (concentration study) and pharmacodynamics (efficacy and toxicity effects study) of levetiracetam in pregnant women. The few studies focus on

  • 0 views
  • 12 May, 2022
  • 1 location
Treating Hyperexcitability in AD With Levetiracetam (LeAD)

administration of the antiepileptic medication levetiracetam (LEV) normalizes these measures and improves cognition.

memantine
cognitive impairment
Accepts healthy volunteers
donepezil
positron emission tomography
  • 0 views
  • 25 Jan, 2022
  • 1 location
Effects of Low-dose Levetiracetam on Clinical Symptoms, Cognition and Hippocampal Hyperactivity in Schizophrenia

Levetiracetam (LEV: (S)-α-ethyl-2-oxo-pyrrolidine acetamide) is an anticonvulsant/antiepileptic drug. The specific aim of this study is to assess the efficacy of low-dose LEV in reducing

schizoaffective disorder
  • 69 views
  • 27 Apr, 2022
  • 1 location
Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia

This study plans to learn more about the effects of levetiracetam (LEV) on brain activity and cognition in schizophrenia and schizoaffective disorder. Levetiracetam is an anti-seizure drug, also

schizoaffective disorder
Accepts healthy volunteers
  • 68 views
  • 25 Mar, 2022
  • 1 location
Generating Evidence on NonEpileptic Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hematomas

cortical depression in other conditions (migraine, subarachnoid hemorrhage). In contrast, some other drugs (Levetiracetam) were not proved to be efficient. Knowing that, the investigators want to compare

  • 0 views
  • 07 May, 2021
  • 1 location
Seizure Treatment in Glioma (STING)

patients. The overall aim of this randomized controlled trial is to directly compare the effectiveness of treatment with levetiracetam or valproic acid in glioma patients with a first seizure.

levetiracetam
astrocytoma, anaplastic
oligodendroglioma
glioblastoma multiforme
astrocytoma
  • 9 views
  • 28 Feb, 2022
  • 4 locations
Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease (TRIP)

The present study is a proof-of-concept clinical trial to test the efficacy of low doses of a repurposed anti-epileptic drug (levetiracetam) in treating memory problems in Parkinson's disease

dementia
Accepts healthy volunteers
cognitive impairment
  • 0 views
  • 25 Jan, 2022
  • 1 location