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Found 25 clinical trials
Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer (OVELIA)

This is a phase 3, single arm, open-label study evaluating the effectiveness of TOL2506 to suppress ovarian function in premenopausal women with HR+, HER2-negative breast cancer. The study will also aim to assess the safety of TOL2506 in men with HR+ breast cancer. The Screening Period will be conducted in …

estradiol
tamoxifen
adjuvant chemotherapy
letrozole
erbb2
  • 1 views
  • 28 Jul, 2022
  • 24 locations
The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's (LUCINDA)

The LUCINDA Trial is a three-site, phase II, randomized, double-blind, placebo-controlled study of leuprolide acetate (Eligard) in women with Mild Cognitive Impairment or Alzheimer's Disease

cholinesterase
mild cognitive impairment
memantine
mini-mental state examination
alzheimer's disease
  • 47 views
  • 28 Feb, 2022
  • 1 location
Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis

. The test group will receive Elagolix for 60 days prior to starting frozen embryo transfer preparation. The control group will be given leuprolide acetate every 28 days x 2 prior to starting the frozen

follicle stimulating hormone
gonadotropin
gonadotrophin releasing hormone analogue
cavities
infertility
  • 58 views
  • 26 Jan, 2021
  • 1 location
Pharmacokinetic Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty

Exploring the efficacy in Leuprolide 45mg in slowing down or reversing Central Precocious Puberty in girls ages 2-8 and boys ages 2-9.

  • 0 views
  • 08 Nov, 2020
  • 1 location
A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer

The purpose of this study is to establish the maximum tolerable dose of niraparib when combined with prostate stereotactic body radiotherapy (SBRT), abiraterone, leuprolide, and prednisone (the

prednisone
adenocarcinoma of prostate
leuprolide
androgen suppression
adenocarcinoma
  • 0 views
  • 15 Dec, 2021
  • 4 locations
Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer

This phase II trial studies how well antiandrogen therapy (leuprolide, apalutamide, and abiraterone acetate) and stereotactic body radiation therapy (SBRT) works in treating patients with

platelet count
antiandrogen therapy
prostatectomy
leuprolide
adenocarcinoma
  • 5 views
  • 11 Mar, 2022
  • 1 location
SAABR: Single Arm Phase II Study of AR Targeted Therapy + Atezolizumab + GnRH Analog and Stereotactic Body Radiotherapy (SBRT) to the Prostate in Men With Newly Diagnosed Hormone-sensitive Metastatic Prostate Cancer

This study is to find out whether adding the study drug atezolizumab and stereotactic body radiotherapy (SBRT) to standard treatment with abiraterone acetate, prednisone, and Lupron® (leuprolide

platelet count
prednisone
leuprolide
adenocarcinoma
bone scan
  • 0 views
  • 14 Sep, 2022
  • 8 locations
Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors

study drugs involved in this study are: Androgen deprivation therapy (ADT) with a drug of your physician's choice. This may include leuprolide (Lupron), goserelin acetate (Zoladex), or

antiandrogen therapy
docetaxel
metastatic prostate cancer
bone scan
hormone therapy
  • 0 views
  • 20 Apr, 2022
  • 4 locations
Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer

Ra 223 dichloride contains a radioactive substance that collects in the bone and gives off radiation that may kill cancer cells. Hormone therapy using leuprolide acetate or goserelin acetate may

antiandrogen therapy
androgens
digital rectal exam
metastatic prostate cancer
bone scan
  • 2 views
  • 02 Mar, 2022
  • 1 location
Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

a type of targeted therapy. Androgen can cause the growth of prostate tumor cells. Degarelix, leuprolide acetate, bicalutamide, goserelin acetate, and abiraterone lowers the amount of androgen made

  • 0 views
  • 21 Aug, 2021
  • 1 location