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Found 4 clinical trials
Does Montelukast Decrease Post Adenotonsillectomy Pain in Children (Montelukast)

Objective: The purpose of the present study is to evaluate the effectiveness of preoperative Montelukast as an analgesic for adenotonsillectomy Study Design: Randomized controlled double blinded clinical trial. Setting: Cincinnati Children's Hospital Medical Center (CCHMC), Division of Pediatric Otolaryngology, Head and Neck Surgery Methods: Children between the age of 3-8 …

opioid
Accepts healthy volunteers
analgesics
postoperative pain
  • 1 views
  • 28 Feb, 2022
  • 1 location
Effect of Montelukast Versus Co Enzyme in Sepsis

Sepsis is a leading cause of morbidity and mortality in intensive care units. Sepsis is a life-threatening organ dysfunction linked to a dysregulated host response to infection. It leads to overwhelming of systemic inflammation causing release of proinflammatory cytokines, which trigger overproduction of reactive oxygen species. Several animal studies with …

fever
cytokines
resuscitation
antioxidants
antibiotics
  • 0 views
  • 10 Apr, 2022
Pediatric Arm of DZL All Age Asthma Cohort

Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood. Therefore, deciphering underlying determinants for different childhood and adult asthma phenotypes is urgently needed to develop personalized treatment approaches targeting distinct underlying mechanisms. Thereby, secondary …

asthma
wheezing
secondary prevention
  • 89 views
  • 29 Jan, 2021
  • 6 locations
Functional Lung MRI for Early Treatment Response Assessment for Patients With Eosinophilic Asthma

Patients with severe eosinophilic asthma will be placed on biologics if they continue to be uncontrolled despite maximized inhalation therapy or if they are only controlled under oral corticosteroids. Among biologics, 80% of patients respond to treatment and improve clinically, but approximately 20% are non-responders and up to date no …

  • 0 views
  • 04 Sep, 2021
  • 1 location