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Found 128 clinical trials
dENdritic Cell Therapy Combined With SURgEry in Mesothelioma (ENSURE)

following first-line chemotherapy. Before standard-of-care chemotherapy, a leukapheresis will be performed and monocytes will be used for differentiation to dendritic cells (DCs) using specific cytokines

  • 0 views
  • 21 Apr, 2022
  • 1 location
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

) catheter will be placed in a large vein in the chest. Participants will have leukapheresis. Blood will be removed through a needle in an arm. A machine will divide the blood and collect white blood

gemcitabine
metastasis
5-fluorouracil
cancer
lung cancer
  • 14 views
  • 10 Aug, 2022
  • 1 location
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

protocol, participants will: Be screened Have cells harvested and grown Have leukapheresis In this protocol, participants will have the procedures below. Participants

gemcitabine
metastasis
5-fluorouracil
cancer
lung cancer
  • 31 views
  • 14 Sep, 2022
  • 1 location
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to Patients With CD70-Expressing Cancers

other tests. They may by admitted to the hospital. Leukapheresis will be performed. For this, blood is removed through a needle in the arm. A machine separates the white blood cells. The rest of the

white blood cell count
metastasis
cancer
systemic therapy
chemotherapy drugs
  • 70 views
  • 19 Sep, 2022
  • 1 location
A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated Cancers

, including imaging procedures, heart and lung tests, and lab tests. They will have a large catheter inserted into a vein. Participants will have leukapheresis. Blood will be removed through a needle

human papillomavirus
metastasis
chemotherapy regimen
cancer
chemotherapy drugs
  • 370 views
  • 16 Sep, 2022
  • 1 location
A Randomized, Double-Blind, Placebo-Controlled Study of a Single Dose of Pembrolizumab in HIV-Infected Patients

leukapheresis. Blood will be removed through a needle in one arm. A machine will remove white blood cells. The rest of the blood will be returned into the other arm. Participants will have a baseline

HIV Vaccine
white blood cell count
antiviral drugs
progestin
hormonal contraception
  • 215 views
  • 18 Sep, 2022
  • 1 location
A Phase I Study of HERV-E TCR Transduced Autologous T Cells in Patients With Metastatic Clear Cell Renal Cell Carcinoma

blood and urine tests. They may have: Scans Heart, lung, and eye tests Lab tests Tumor samples taken Participants will have leukapheresis. Blood

neutrophil count
denosumab
white blood cell count
tumor cells
treatment regimen
  • 73 views
  • 22 Sep, 2022
  • 1 location
Clinical Trial With Donor Modified Immune Cells in Living Donor Kidney Transplantation

product MIC for the patients in the MIC therapy group mononuclear cells of the peripheral blood are obtained from the donors in a leukapheresis procedure. In the subsequent treatment phase, the patients

bilateral oophorectomy
hormone replacement therapy (hrt)
tubal ligation
hysterectomy
immunosuppressants
  • 0 views
  • 23 May, 2022
  • 1 location
DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab (DERIVe)

Patients with newly diagnosed glioblastoma will be consented following tumor resection then undergo leukapheresis for harvest of peripheral blood leukocytes for generation of dendritic cells

temozolomide
mgmt gene
tumour resection
MRI
  • 12 views
  • 09 Jun, 2022
  • 1 location
Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant

neurologic evaluation and fill out questionnaires. Participants will have leukapheresis. Blood will be removed from the participant. A machine will divide whole blood into red cells, plasma, and

  • 0 views
  • 23 Jul, 2022
  • 1 location