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Found 128 clinical trials
Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells From Patients With DOCK8 Deficiency, LAD-1, and GATA2 Deficiency

injections at the National Institutes of Health Clinical Center. On day 5, participants will have a single leukapheresis procedure to collect the stem cells from the blood. No

  • 0 views
  • 16 Sep, 2022
  • 1 location
Novel Genetic Disorders of the Immune System

biopsy punch is inserted into the skin and rotated. A small circle of skin is removed. Participants 10 and older may also choose to have leukapheresis. Blood is taken through a needle in one

  • 0 views
  • 18 Sep, 2022
  • 1 location
Natural History of Anthrax: A Study of Primary Infected, Recovered, and Exposed (SPoRE) Individuals and Evaluation of AVA Vaccinated Recipients

have the following optional research procedures a) leukapheresis or plasmapheresis (see description under non-infected, vaccinated individuals above

antibiotics
diarrhea
septicemia
inhalational anthrax
anthrax vaccine adsorbed
  • 13 views
  • 20 Sep, 2022
  • 1 location
Genetic Studies of Chronic Active Epstein-Barr Virus Infection

counts, blood chemistry, EBV serologies, and viral load. Other tests, such as CT scan or MRI, may be performed if medically indicated. Patients will be asked to undergo leukapheresis. In vitro

  • 73 views
  • 14 Sep, 2022
  • 1 location
Host Response to Infection and Treatment in the Filarial Diseases of Humans

site is monitored for swelling or hives in the next 48 hours. Leukapheresis (only on patients 21 or older ) to collect quantities of white blood cells. Whole blood is collected through a

heart disease
diethylcarbamazine
blindness
swelling
ivermectin
  • 72 views
  • 22 Sep, 2022
  • 1 location
Ex Vivo Characterization and Targeting of the Latent HIV Infected Reservoir to Cure HIV (EX VIVO)

Combination antiretroviral therapy (cART) blocks intracellular human immunodeficiency virus (HIV) replication in CD4+ T-lymphocytes, but fails to eliminate latent HIV infected CD4+ T-lymphocytes. About 7 (range <1-100) in 106 of these cells are latently infected and can cause reactivation of proviral HIV when cART is stopped. These latently infected cells …

antiretroviral therapy
antiretroviral
immunodeficiency
  • 0 views
  • 23 Mar, 2022
  • 1 location
Paradoxical Tuberculosis Reactions in Patients Without HIV Infection

Background Most people with tuberculosis (TB) feel better after starting treatment. But for some people, the opposite happens. They may feel better at first, but then suddenly get worse. This is a paradoxical reaction. Researchers want to better understand what causes this reaction and what happens after someone has it. …

HIV Infection
  • 0 views
  • 29 Jul, 2022
  • 1 location
Evaluation of Viral Factors and Immune Parameters to Study HIV-Specific Immunity

This study will collect white blood cells and plasma for research on how the immune system controls HIV infection. The immune system of a very small group of HIV-infected patients, called non-progressors, has been able to control HIV for long periods without antiretroviral therapy. Some immune system-related genes important for …

antiretroviral agents
white blood cell count
opportunistic infection
abacavir
leukapheresis
  • 90 views
  • 22 Sep, 2022
  • 1 location