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Found 122 clinical trials
The Characterization of CD34+ Derived Mast Cell Precursors

, and blood tests to assess general health status Days 2 through 6 Daily injections under the skin of G-CSF a hormone that stimulates white blood cell production Day 7 Leukapheresis

blood test
kidney function tests
Accepts healthy volunteers
  • 124 views
  • 28 Oct, 2022
  • 1 location
Clinical Specimen Collection From Pompe Disease Patients

specimen (approximately 20mL) to be used in preclinical studies and research and development of FTX-PD01. Subjects may eventually be asked to undergo mobilized leukapheresis for bone marrow stem cell

gene therapy
  • 0 views
  • 03 Jun, 2022
  • 1 location
Evaluation, Treatment, and Follow-up of Patients With Lyme Disease

kilogram (2.2 pounds) of body weight for children under 18 years of age. Leukapheresis to collect large numbers of white blood cells. Whole blood is collected through a needle in an arm vein

skin biopsy
tissue cultures
  • 1428 views
  • 21 Oct, 2022
  • 1 location
Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy

volunteers to perform research studies. To do this, they are collecting lymphocytes through leukapheresis. Objectives To collect healthy cells from volunteers for

systolic blood pressure
Accepts healthy volunteers
hepatitis b
diastolic blood pressure
cancer
  • 265 views
  • 22 Oct, 2022
  • 1 location
Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells From Patients With DOCK8 Deficiency, LAD-1, and GATA2 Deficiency

injections at the National Institutes of Health Clinical Center. On day 5, participants will have a single leukapheresis procedure to collect the stem cells from the blood. No

  • 0 views
  • 21 Oct, 2022
  • 1 location
Novel Genetic Disorders of the Immune System

biopsy punch is inserted into the skin and rotated. A small circle of skin is removed. Participants 10 and older may also choose to have leukapheresis. Blood is taken through a needle in one

  • 0 views
  • 14 Oct, 2022
  • 1 location
Natural History of Anthrax: A Study of Primary Infected, Recovered, and Exposed (SPoRE) Individuals and Evaluation of AVA Vaccinated Recipients

have the following optional research procedures a) leukapheresis or plasmapheresis (see description under non-infected, vaccinated individuals above

diarrhea
spinning
antibiotic therapy
vaccination
lymph node biopsy
  • 13 views
  • 25 Oct, 2022
  • 1 location
Genetic Studies of Chronic Active Epstein-Barr Virus Infection

counts, blood chemistry, EBV serologies, and viral load. Other tests, such as CT scan or MRI, may be performed if medically indicated. Patients will be asked to undergo leukapheresis. In vitro

  • 73 views
  • 20 Oct, 2022
  • 1 location
Host Response to Infection and Treatment in the Filarial Diseases of Humans

site is monitored for swelling or hives in the next 48 hours. Leukapheresis (only on patients 21 or older ) to collect quantities of white blood cells. Whole blood is collected through a

swelling
diethylcarbamazine
sedative
ivermectin
heart disease
  • 72 views
  • 28 Oct, 2022
  • 1 location
Ex Vivo Characterization and Targeting of the Latent HIV Infected Reservoir to Cure HIV (EX VIVO)

Combination antiretroviral therapy (cART) blocks intracellular human immunodeficiency virus (HIV) replication in CD4+ T-lymphocytes, but fails to eliminate latent HIV infected CD4+ T-lymphocytes. About 7 (range <1-100) in 106 of these cells are latently infected and can cause reactivation of proviral HIV when cART is stopped. These latently infected cells …

immunodeficiency
antiretroviral
antiretroviral therapy
  • 0 views
  • 23 Mar, 2022
  • 1 location