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Found 106 clinical trials
HAIC Versus Systemic Chemotherapy for Unresectable ICC

The purpose of this study is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) of irinotecan, oxaliplatin, 5-fluorouracil and leucovorin compared systemic

cholangiocarcinoma
gemcitabine
local ablative therapy
cirrhosis
irinotecan
  • 0 views
  • 19 Feb, 2022
  • 2 locations
HAIC With FOLFOX Versus Systemic Chemotherapy With GP for Unresectable ICC

The purpose of this study is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) of oxaliplatin, 5-fluorouracil and leucovorin compared systemic chemotherapy of

gemcitabine
platelet count
neutrophil count
folfox
pet scan
  • 0 views
  • 26 Jul, 2021
  • 1 location
HAIC Combined With Lenvatinib and Sintilimab for Hepatocellular Carcinoma With PVTT

This study intends to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy of oxaliplatin, 5-fluorouracil and leucovorin plus lenvatinib and Sintilimab for patients

  • 0 views
  • 26 Jan, 2021
  • 1 location
NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer

This phase II trial evaluates whether early switching from modified fluorouracil/irinotecan/leucovorin/oxaliplatin (mFOLFIRINOX) chemotherapy regimen to a combination of gemcitabine and nab

  • 0 views
  • 22 Mar, 2022
  • 1 location
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

This phase II trial studies how well ramucirumab and paclitaxel or the FOLFIRI regimen (leucovorin calcium, fluorouracil, and irinotecan hydrochloride) work in treating patients with small bowel

  • 12 views
  • 14 Nov, 2021
  • 448 locations
Trial of Infusional FOLFIRINOX in First Line Treatment of Advanced Biliary Tract Cancers (FBI-TRAC)

This study is to evaluate the response rate and toxicity profile of infusional 5 fluorouracil, leucovorin, oxaliplatin and irinotecan (FOLFIRINOX) in first-line treatment of advanced biliary

leucovorin
Accepts healthy volunteers
irinotecan
platelet count
renal function
  • 5 views
  • 25 Feb, 2022
  • 1 location
A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

commonly used to treat CRC (leucovorin, oxaliplatin, irinotecan, bevacizumab, cetuximab and panitumumab). The primary objective is to identify a recommended dose and schedule for NUC-3373 when combined

leucovorin
panitumumab
metastatic colorectal cancer
irinotecan
combinations
  • 17 views
  • 22 Mar, 2022
  • 6 locations
Induction FLOT With CROSS CRT for Esophageal Cancer

This study evaluates a novel regimen of induction chemotherapy using a combination of docetaxel, oxaliplatin, and leucovorin, with short term infusional 5-FU (FLOT), given prior to

progestogen
adjuvant therapy
oophorectomy
esophageal cancer
paclitaxel
  • 0 views
  • 17 Mar, 2022
  • 3 locations
Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy

dose adjustment algorithm for reducing unplanned delays in patients receiving FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin)-type chemotherapy, while maintaining acceptable chemotherapy dose

leucovorin
cancer chemotherapy
folfox regimen
bevacizumab
panitumumab
  • 0 views
  • 06 Nov, 2021
  • 1 location
HAIC of Oxaliplatin and 2400 mg/m 5-fu vs HAIC of Oxaliplatin and 1200 mg/m 5-fu for Unresectable HCC: a Randomised Phase 3 Non-inferiority Trial

Hepatic artery infusion of oxaliplatin, leucovorin and 2400 mg/m fluorouracil is effective in hepatocellular carcinoma. However, SILIUS study showed that sorafenib plus hepatic artery infusion

  • 0 views
  • 27 Jan, 2021
  • 3 locations