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Found 87 clinical trials
Featured trial
TOL2506A: A Phase 3, Single Arm, Open-Label Study Evaluating Ovarian Suppression Following Three-Month Leuprolide Acetate For Injectable Suspension (TOL2506) in Combination with Endocrine Therapy in Premenopausal Subjects with Hormone-Receptor–Positive (HR+), Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer

those who will initiate therapy with an AI (letrozole, anastrozole, or exemestane) beginning 6 weeks after the first administration of TOL2506, upon confirmation that estradiol (E2) levels of < 20 pg

erbb2
HER2
endocrine therapy
tamoxifen
letrozole
  • 0 views
  • 07 Jan, 2022
  • 1 location
Featured trial
CALGB 40903: A Phase II Study of Neoadjuvant Letrozole for Postmenopausal Women with Estrogen Receptor Positive Ductal Carcinoma in Situ (DCIS)

CALGB 40903: A Phase II Study of Neoadjuvant Letrozole for Postmenopausal Women with Estrogen Receptor Positive Ductal Carcinoma in Situ (DCIS)

  • 340 views
  • 08 Nov, 2020
  • 1 location
Controlled Ovarian Stimulation in Newly Diagnosed Breast Cancer PatiEnts (fAMHOPE) (fAMHOPE)

refining the understanding of the efficacy and safety of controlled ovarian stimulation with or without letrozole in young women with newly diagnosed breast cancer who are candidates to receive (neo

breast cancer
breast carcinoma
adjuvant chemotherapy
cancer
stage iv breast cancer
  • 0 views
  • 28 Feb, 2022
  • 1 location
Ribociclib and Letrozole Treatment in Ovarian Cancer

The study evaluates the response to treatment with Ribociclib and Letrozole in patients with low grade serous cancer of the ovary, fallopian tube or peritoneum.

  • 152 views
  • 26 Mar, 2022
  • 27 locations
Letrozole in Induction of Abortion of Anembryonic Pregnancy

of letrozole combined with misoprostol versus using misoprostol alone in inducing complete abortion in patients with blighted ovum.

  • 0 views
  • 24 Mar, 2022
  • 1 location
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome

Polycystic ovary syndrome accounts for the vast majority of anovulatory symptoms and hyperandrogenism in women. The diagnosis of Polycystic ovary syndrome has life-long implications, with increased risk for infertility, metabolic syndrome, and type 2 diabetes mellitus, and possibly for cardiovascular disease and endometrial carcinoma. Polycystic ovary syndrome is diagnosed in …

polycystic ovary syndrome
clomiphene
endometrial carcinoma
cardiovascular disease
metformin
  • 228 views
  • 12 May, 2022
  • 1 location
Palbociclib Letrozole & Venetoclax in ER and BCL-2 Positive Breast Cancer

This study is investigating the combination of palbociclib, letrozole and venetoclax in ER and BCL-2 positive locally advanced or metastatic breast cancer. It is hypothesised that

gilbert's syndrome
breast cancer
carcinoma
neutrophil count
metastasis
  • 45 views
  • 24 Jan, 2021
  • 3 locations
Letrozole Combined With Anlotinib Hydrochloride in the Treatment of Platinum-resistant Recurrent Ovarian Cancer

The study is a prospective, single-arm, open label, exploratory phase 2 clinical trial, which aims to study the therapeutic effect of letrozole combined with anlotinib hydrochloride in platinum

  • 0 views
  • 28 Jan, 2021
  • 1 location
Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients

Phase II, randomized, open-label, international, multicenter study to compare efficacy of standard chemotherapy vs. letrozole plus abemaciclib as neoadjuvant therapy in HR-positive/HER2-negative

  • 0 views
  • 19 Nov, 2021
  • 28 locations
Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer

acquisition, study participants will take a 7- to 56-day (1-8 weeks) course of letrozole in accordance with standard of care. They will then undergo definitive surgical resection of their primary tumor

lumpectomy
breast cancer
breast carcinoma
renal function
tamoxifen
  • 12 views
  • 22 Apr, 2022
  • 1 location