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Found 20 clinical trials
Longitudinal Study of the Intestinal Cutaneous and Salivary Microbiota in Children With Food-induced Enterocolitis Syndrome (SEIPA)

Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non IgE-mediated allergy, presenting with vomiting, and may be complicated by hypovolemic shock. The pathophysiology of FPIES is not well characterized and there is no biological marker confirming the diagnosis or predicting recovery. Gut microbiota in IgE-mediated allergy is pro-inflammatory and the addition …

  • 0 views
  • 13 Aug, 2021
Longitudinal Study of Urea Cycle Disorders

Urea cycle disorders (UCD) are a group of rare inherited metabolism disorders. Infants and children with UCD commonly experience episodes of vomiting, lethargy, and coma. The purpose of this

hyperargininemia
citrullinemia
arginine
citrulline
vomiting
  • 98 views
  • 24 Apr, 2021
  • 16 locations
Dietary Rehabilitation in Severely Acutely Malnourished Children

, hepatomegaly, lethargy, anorexia, anemia, severe immune deficiency and rapid progression to mortality characterize a state commonly coined as "complicated SAM". Kwashiorkor is one of the forms of complicated

  • 0 views
  • 06 Sep, 2021
  • 1 location
Clinical Characteristics of Acutely Hospitalized Adults With Acute Pyelonephritis

Acute pyelonephritis is an acute infection. Today the diagnosis is made primarily on the basis of unspecific clinical symptoms with flank tenderness combined with as a key clue. This study will investigate which clinical and paraclinical characteristics available within 4 hours of hospital stay, that describes the patients admitted in …

  • 0 views
  • 15 Mar, 2021
  • 1 location
Brain Biomarkers Study

Ammonia is a waste product of protein and amino acid catabolism and is also a potent neurotoxin. High blood ammonia levels on the brain can manifest as cytotoxic brain edema and vascular compromise leading to intellectual and developmental disabilities. The following aims are proposed: Aim 1 of this study will …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Accuracy of Infection Biomarkers in the Investigation of Patients With Suspected Acute Pyelonephritis

The aim of this study is to investigate the diagnostic and prognostic value of C-reactive protein (CRP), serum procalcitonin (PCT) and soluble urokinase plasminogen activator receptor (suPAR) in the initial investigation of patients hospitalized with suspected acute pyelonephritis (APN).

  • 0 views
  • 12 Mar, 2021
  • 1 location
COVID-19 in Pediatric Oncology and Hematology Centers in France

Since the description of the first cases of infection in December 2019 in the Hubei province in China, a new coronavirus, called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), emerged and caused a pandemic. This new virus is responsible for an infectious disease with respiratory and potent severe symptoms, called …

diarrhea
chest ct
cancer
myalgia
immunosuppressive agents
  • 0 views
  • 25 Jan, 2021
  • 1 location
Glucocorticoid Withdrawal Syndrome in Patients With Treated Cushing Syndrome

Cushing syndrome (CS) is an endocrine disorder caused by chronic exposure to glucocorticoid (GC) excess. Endogenous CS has an estimated incidence of 0.2 to 5.0 cases per million per year and prevalence of 39 to 79 cases per million in various populations. CS usually affects young women, with a median …

  • 0 views
  • 26 Jan, 2021
Identification Genetic Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung Disease

To identify demographic, clinical, genetic, immunologic and/or microbial (i.e., fecal stream characterization) risk factors that influence the likelihood of development of the HAEC phenotype in children who carry the diagnosis of HD. The newly formed HAEC Collaborative Research Group (HCRG) will utilize the 4 participating centers in the current consortia …

  • 73 views
  • 21 Jan, 2021
  • 1 location
Quality of Life and Eating Disorders in Children With FPIES Food Allergy or Celiac Disease

Food allergies are associated with a decrease in quality of life. Patients with FPIES often have more food avoidance than necessary. The greater the number of avoided foods, the greater the risk of eating disorders. To date, no study about quality of life or assessment of eating difficulties has been …

  • 8 views
  • 13 Aug, 2021