Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 39 clinical trials
Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

leiomyosarcoma. Researchers want to see if a combination of drugs can help. Objective To find a safe dose of pomalidomide plus nivolumab in people with cancers caused by

etoposide
herpes
cancer
ct scan
antiretroviral therapy
  • 0 views
  • 13 Jun, 2022
  • 1 location
A Phase 1/2 Study of CYT-0851, an Oral RAD51 Inhibitor, in B-Cell Malignancies and Advanced Solid Tumors

This clinical trial is an interventional, active-treatment, open-label, multi-center, Phase 1/2 study. The study objectives are to assess the safety, tolerability and pharmacokinetics (PK) of the oral RAD51 inhibitor CYT-0851 in patients with relapsed/refractory B-cell malignancies and advanced solid tumors and to identify a recommended Phase 2 dose as a …

stage iv breast cancer
cancer
breast cancer
multiple myeloma
solid neoplasm
  • 317 views
  • 25 Feb, 2022
  • 18 locations
Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas (ImmunoSarc)

undifferentiated pleomorphic sarcoma and of the doxorubicin + dacarbazine + nivolumab combination in leiomyosarcoma. Treatment Cohort 7a dose level 0: Patients will receive

methotrexate
anthracyclines
angiogenesis inhibitor
solitary fibrous tumor
alveolar soft part sarcoma
  • 94 views
  • 25 Feb, 2022
  • 13 locations
Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc) (Stereosarc)

have been obtained in several sarcomas with acceptable tolerance. Preliminary clinical experience suggests that immunotherapy can be efficient in refractory leiomyosarcomas. Several drugs targeting

ipilimumab
leiomyosarcoma
soft tissue sarcoma
tumor cells
liposarcoma
  • 0 views
  • 22 Mar, 2022
  • 1 location
MYometrial Lesion UltrasouNd And mRi (MYLUNAR)

A monocentric prospective observational study aimed at assessing the accuracy of a diagnostic algorithm to pre-operatively identify uterine sarcomas.. Primary Aim:The primary outcome is to evaluate the accuracy (sensitivity/specificity) of "Positive Orange Criteria" category in predicting uterine sarcoma and STUMP in the population of patients with > 3 cm myometrial …

  • 0 views
  • 17 Feb, 2022
  • 1 location
REtroperitoneal SArcoma Registry: an International Prospective Initiative

Surgery is currently the only potentially curative treatment modality for localized retroperitoneal sarcoma (RPS). Available studies regarding oncologic outcomes are mainly retrospective in nature, and RPS are recognized as a rare disease. Therefore, prospective analysis of high quality data is a top priority. Primary Objectives of this study are: to …

  • 0 views
  • 22 Jan, 2021
  • 16 locations
Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas

indication for diagnosis of myometrial tumors: leiomyomas and/or leiomyosarcomas. Recently, Next Generation Sequencing (NGS) technology has been successfully applied in different areas of knowledge

ct scan
leiomyosarcoma
leiomyoma
uterine myomectomy
myomectomy
  • 55 views
  • 12 Sep, 2021
  • 4 locations
Accuracy of the Preoperative Molecular Diagnosis of Uterine Tumors by Liquid Biopsy

suspected benign tumours should be considered at risk for occult leiomyosarcoma. Recently, the concept of "liquid biopsy" has emerged as a minimally invasive alternative to surgical biopsies for

leiomyoma
hysterectomy
  • 0 views
  • 18 Sep, 2021
  • 18 locations
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures …

other disease
rare diseases
  • 4 views
  • 25 Jan, 2022
  • 2 locations