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Found 41 clinical trials
Avelumab in Combination With Gemcitabine in Advanced Leiomyosarcoma as a Second-line Treatment

A Phase 2 trial of avelumab plus gemcitabine in advanced leiomyosarcoma as a second line treatment

  • 0 views
  • 11 Feb, 2021
  • 7 locations
Pazopanib vs. Pazopanib Plus Gemcitabine (PazoDoble)

leiomyosarcomas or other metastatic uterine tumours.

  • 2 views
  • 12 Feb, 2022
  • 3 locations
Phase II Study of Regorafenib as Maintenance Therapy

Multicenter double-blind placebo-controlled randomized Phase II study comparing regorafenib to placebo, as maintenance therapy in metastatic soft-tissue non-adipocytic sarcomas experiencing stable disease or response after 6 cycles of doxorubicin-based chemotherapy as 1st line chemotherapy.

  • 2 views
  • 08 Feb, 2022
  • 18 locations
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) (APROMISS)

THIS STUDY IS CURRENTLY RECRUITING PATIENTS WITH ALVEOLAR SOFT PART SARCOMA ONLY AND IS NO LONGER RECRUITING PATIENTS WITH SYNOVIAL SARCOMA OR LEIOMYOSARCOMA.

alveolar soft part sarcoma
systemic therapy
anlotinib
ejection fraction
kidney function tests
  • 334 views
  • 27 Jan, 2022
  • 22 locations
Surgery With Our Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

(dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. After confirmation of eligibility criteria, patients will be randomized to either the standard arm or

dedifferentiated liposarcoma
systemic therapy
EGFR
neutrophil count
measurable disease
  • 0 views
  • 30 Jul, 2021
  • 23 locations
Nanatinostat Plus Valganciclovir in Patients With Advanced EBV+ Solid Tumors, and in Combination With Pembrolizumab in EBV+ RM-NPC

This study will evaluate the safety efficacy of nanatinostat in combination with valganciclovir in patients with relapsed/refractory EBV-positive solid tumors and in combination with pembrolizumab in patients with recurrent/metastatic nasopharyngeal carcinoma

carcinoma
measurable disease
metastatic nasopharyngeal carcinoma
platinum-based chemotherapy
chemotherapy regimen
  • 0 views
  • 24 Jul, 2022
  • 12 locations
A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases

The purpose of this study is to assess the efficacy and safety of tabelecleucel in participants with Epstein-Barr virus (EBV) associated diseases.

colony stimulating factor
hypogammaglobulinemia
bone marrow procedure
measurable disease
cancer
  • 1 views
  • 21 Jul, 2022
  • 37 locations
Lurbinectedin + Doxorubicin In Leiomyosarcoma

lurbinectedin with doxorubicin in people with soft tissue sarcoma. The second part is a randomized study to determine which is more effective at treating leiomyosarcoma, lurbinectedin with doxorubicin or

  • 0 views
  • 23 Mar, 2022
  • 2 locations
Metronomic Trabectedin Gemcitabine and Dacarbazine for Leiomyosarcoma

This is an open label phase 2 study using metronomic doses of trabectedin, gemcitabine and dacarbazine given intravenously.

trabectedin
leiomyosarcoma
kidney function tests
measurable disease
gemcitabine
  • 0 views
  • 24 Sep, 2021
  • 1 location
A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma

The purpose of this study is to find out whether combining the study drugs rucaparib and nivolumab may be an effective treatment for advanced and/or metastatic LMS, and whether the study treatment works as well as the standard chemotherapy for this type of cancer.

EGFR
systemic therapy
neutrophil count
measurable disease
cancer
  • 0 views
  • 29 Sep, 2021
  • 7 locations