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Found 40 clinical trials
Avelumab in Combination With Gemcitabine in Advanced Leiomyosarcoma as a Second-line Treatment

A Phase 2 trial of avelumab plus gemcitabine in advanced leiomyosarcoma as a second line treatment

  • 0 views
  • 11 Feb, 2021
  • 7 locations
Pazopanib vs. Pazopanib Plus Gemcitabine (PazoDoble)

leiomyosarcomas or other metastatic uterine tumours.

  • 2 views
  • 12 Feb, 2022
  • 3 locations
Phase II Study of Regorafenib as Maintenance Therapy

Multicenter double-blind placebo-controlled randomized Phase II study comparing regorafenib to placebo, as maintenance therapy in metastatic soft-tissue non-adipocytic sarcomas experiencing stable disease or response after 6 cycles of doxorubicin-based chemotherapy as 1st line chemotherapy.

  • 2 views
  • 08 Feb, 2022
  • 18 locations
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) (APROMISS)

THIS STUDY IS CURRENTLY RECRUITING PATIENTS WITH ALVEOLAR SOFT PART SARCOMA ONLY AND IS NO LONGER RECRUITING PATIENTS WITH SYNOVIAL SARCOMA OR LEIOMYOSARCOMA.

systemic therapy
cancer
renal function
synovial sarcoma
dacarbazine
  • 334 views
  • 27 Jan, 2022
  • 22 locations
Surgery With Our Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

(dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. After confirmation of eligibility criteria, patients will be randomized to either the standard arm or

ifosfamide
systemic therapy
cancer
tubal occlusion
EGFR
  • 0 views
  • 30 Jul, 2021
  • 23 locations
Nanatinostat Plus Valganciclovir in Patients With Advanced EBV+ Solid Tumors, and in Combination With Pembrolizumab in EBV+ RM-NPC

This study will evaluate the safety efficacy of nanatinostat in combination with valganciclovir in patients with relapsed/refractory EBV-positive solid tumors and in combination with pembrolizumab in patients with recurrent/metastatic nasopharyngeal carcinoma

metastatic nasopharyngeal carcinoma
measurable disease
chemotherapy regimen
platinum-based chemotherapy
nasopharyngeal carcinoma
  • 0 views
  • 09 Apr, 2022
  • 6 locations
A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases

The purpose of this study is to assess the efficacy and safety of tabelecleucel in participants with Epstein-Barr virus (EBV) associated diseases.

systemic disease
cancer
rituximab
colony stimulating factor
measurable disease
  • 1 views
  • 10 May, 2022
  • 26 locations
Lurbinectedin + Doxorubicin In Leiomyosarcoma

lurbinectedin with doxorubicin in people with soft tissue sarcoma. The second part is a randomized study to determine which is more effective at treating leiomyosarcoma, lurbinectedin with doxorubicin or

  • 0 views
  • 23 Mar, 2022
  • 2 locations
Metronomic Trabectedin Gemcitabine and Dacarbazine for Leiomyosarcoma

This is an open label phase 2 study using metronomic doses of trabectedin, gemcitabine and dacarbazine given intravenously.

dacarbazine
measurable disease
trabectedin
platelet count
leiomyosarcoma
  • 0 views
  • 24 Sep, 2021
  • 1 location
CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma

The purpose of this study is to find out if giving a dose of heated chemotherapy in the abdomen immediately after surgery that is done to remove uterine leiomyosarcoma type of cancer will help

  • 0 views
  • 24 Mar, 2022
  • 1 location