Found 18 clinical trials
Impact of Preoperative Myocardial Fibrosis Related to Mitral Valve Prolapse on Postoperative Left Ventricular Remodeling (IMPARED)
Primary mitral regurgitation (MR) is the most common valvular disease in western countries. The MR mechanism is often related to a mitral valve prolapse (MVP) defined as a single or bi-leaflet prolapse of at least 2 mm beyond the long-axis mitral annular plane. In recent years, several studies have identified …
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- 04 Oct, 2022
- 1 location
Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair
The investigators' hypothesis is that CMR tissue characterization and myocardial function analysis acquired by CMR feature tracking technique predict reverse remodeling in patients with severe secondary mitral regurgitation (MR) undergoing transcatheter mitral edge-to-edge repair.
- 0 views
- 05 Sep, 2021
- 1 location
Percutaneous Revascularization in Infarction With Late Presentation and Absence of Viability: Effects on Left Ventricular Remodeling and Contractility
The purpose of this study is to evaluate whether late recanalization in patients with ST elevation myocardial infarction (STEMI) without Viability on Cardiovascular Magnetic Resonance Image (MRI) can reduce the reverse remodeling through the reduction of the End Systolic Volume (ESV) at 6 months.
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- 26 Mar, 2022
- 1 location
Effect of Dapagliflozin on LV Remodeling Post AMI
The overall hypothesis of the study is that Dapagliflozin will reduce left ventricular remodeling in patients who have had a myocardial infarction.
- 0 views
- 16 Mar, 2021
- 1 location
Open Label RCT for Chronic Severe AR : Entresto vs. CCB/ARB (REVERSE-AR)
The purpose of this study is to assess the efficacy of sacubitril-valsartan compared to the combination of ARB/CCB on left ventricular remodeling in patients with chronic aortic valve
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- 23 Mar, 2022
- 1 location
Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis
suggest a more clinical approach to cardiac elastography. This study propose to compare myocardial stiffness of a group of coronary bypass patients without hypertrophic left ventricular remodeling or
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- 08 Oct, 2021
- 2 locations
Angiotensin Receptor Blockers in Aortic Stenosis (ARBAS)
This study is intended to investigate the effect of angiotensin receptor blockers (ARBs) on mild-to-moderate aortic stenosis.
- 0 views
- 21 Apr, 2022
- 2 locations
LVAD Conditioning for Cardiac Recovery
The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol. During myocardial conditioning, LVAD speed is reduced gradually in order to increase the work load of the …
- 13 views
- 11 Jul, 2022
- 1 location
Deferred Stenting in Patients With Anterior Wall STEMI (INNOVATIONCORE)
Trial Name) Impact of Immediate SteNt ImplaNtatiOn Versus Deferred Stent ImplAntaTION on Clinical Outcomes in Patients with AnteRior Wall ST-segment Elevation Myocardial Infarction (INNOVATION-CORE) Objectives) To evaluate the impact of deferred versus immediate stenting in patients with acute ST-segment elevation anterior wall myocardial infarction (STEMI) on the clinical efficacy and …
- 6 views
- 01 Feb, 2022
- 1 location
Stress CMR in Patients With Coronary Chronic Total Occlusions (CARISMA_CTO)
CMR could identify patients who are more likely to benefit from PCI in terms of improvement in left ventricular remodeling, functional recovery and clinical outcome.
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- 25 Feb, 2022
- 1 location
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