Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 23 clinical trials
Evaluation od Safety and Performance of the Omega™ LAA (Left Atrial Appendage) Occluder and Omega™ Delivery System in Patients With Non-Valvular Atrial Fibrillation and High Bleeding Risk (Omega)

The purpose of the study is to assess the safety and performance of the Omega™ LAA (Left Atrial Appendage) Occluder and Omega™ Delivery System in LAA (Left Atrial Appendage) closure for patients

  • 9 views
  • 06 Apr, 2022
  • 3 locations
K2 Medical KALPA X™ Mapping, Imaging and Navigation Device

evaluate the safety and performance of the KALPA™ mapping, imaging and navigation device in patients undergoing Left Atrial Appendage Closure (LAAC).

  • 0 views
  • 20 Dec, 2021
  • 1 location
Left Atrial Appendage CLOSURE for the Prevention of Thromboembolisms in Patients Undergoing Aortic Bioprosthesis Surgery

The primary purpose of the LAA-CLOSURE trial is to assess the efficacy and safety of surgical closure of LAA in patients undergoing aortic valve replacement. This randomized, prospective, open-label international multicenter trial will enroll 1040 patients undergoing aortic valve replacement with CHA2DS2-VASC score 2 but without an indication for anticoagulation …

heart disease
aortic valve replacement
coronary artery bypass graft
  • 0 views
  • 10 May, 2021
  • 4 locations
Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy (CLOSURE-AF)

The study goal is to determine the clinical benefit of percutaneous catheter-based left atrial appendage (LAA) closure in patients with non-valvular atrial fibrillation (NVAF) at high risk of stroke (CHA2DS2-VASc Score 2) as well as high risk of bleeding as compared to best medical care (including a [non-vitamin K] oral …

anticoagulants
rivaroxaban
phenprocoumon
stroke
edoxaban
  • 13 views
  • 28 Feb, 2022
  • 17 locations
Prevention of Stroke by Left Atrial Appendage Closure in Atrial Fibrillation Patients After Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) in patients with non-valvular atrial fibrillation (NVAF) poses a particular dilemma for thromboprophylaxis. Left atrial appendage occlusion (LAAO) is a non-pharmacological approach to prevent cardiac embolism in NVAF. The risk-benefit ratio of LAAO in patients with NVAF after ICH is unknown. The aim of STROKECLOSE is to …

intracerebral hemorrhage
atrial fibrillation
left atrial appendage occlusion
stroke
fibrillation
  • 1 views
  • 27 Jan, 2022
  • 1 location
CHAMPION-AF Clinical Trial (CHAMPION-AF)

The primary objective of this study is to determine if left atrial appendage closure (LAAC) with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in

heart failure
anticoagulants
transient ischemic attack
diabetes
noac
  • 130 views
  • 14 May, 2022
  • 148 locations
Left Atrium Appendage Closure by Surgery-2

to support the efficacy and safety of this practice. We therefore conducted the Left Atrial Appendage Closure by Surgery (LAACS) study (2010-2016) were patients in whom the appendage was

stroke
traumatic brain injury
fibrillation
atrial fibrillation
heart surgery
  • 0 views
  • 30 Apr, 2021
  • 6 locations
Computational Simulation to Plan for Percutaneous Left Atrial Appendage Closure

To ensure a successful percutaneous left atrial appendage (LAA) closure, it is important to select the correct size of the closure device used for each patient. To define and measure the size of the LAA, 2D transesophageal echocardiography (TEE) has been typically used. An increasing number of hospitals recently switched …

fibrillation
left atrial appendage closure
transesophageal echocardiography
  • 0 views
  • 04 Mar, 2022
  • 1 location
The Role of Multimodality Imaging in Left Atrial Appendage Closure

The aim of the present prospective, randomized single-centre study is to determine the utility of multimodal imaging in percutaneous left atrial appendage closure. The investigators are planning

diagnostic procedure
left atrial appendage closure
  • 0 views
  • 16 Nov, 2021
  • 1 location
Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure (ANDES)

The objective of the study is to compare short-term (8 weeks) anticoagulation therapy (DOAC) vs. antiplatelet therapy for the prevention of device thrombosis following transcatheter LAAC.

clot
rivaroxaban
thrombosis
antiplatelet therapy
edoxaban
  • 10 views
  • 14 Feb, 2022
  • 1 location