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Found 32 clinical trials
MRI-guided Focal Laser Ablation Prostate Cancer

Prostate cancer is the most frequent malignancy in the male population of developed countries and has a substantial socio-economic impact. Focal therapies, including focal laser ablation (FLA

  • 30 May, 2022
  • 1 location
Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy (START)

The goal is to provide a novel therapeutic option for temporal lobe epilepsy patients when focal impaired awareness seizures cannot be stopped by medications, surgical or laser ablation, or by

  • 20 Jul, 2022
  • 3 locations
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.

chemotherapy and immunotherapy. Patients with laser ablation-accessible solid tumors are treated by thermal ablation followed immediately by an intratumoral injection of IP-001 (1 % N-dihydro-galacto

  • 24 Apr, 2022
  • 2 locations
A Phase I, Open Label Study Employing the Topical Immunomodulator Diphencyprone to Treat Cutaneous Neurofibromas Associated With NF1

; however, tumor burden may be excessive, tumors do not regress, and they can be disfiguring, painful, and itchy. Currently, the only treatment is surgery or laser ablation; however, outcomes are limited by

  • 14 Sep, 2022
  • 1 location
Collagen Cross-linking in Keratoconus

Optical Coherence Tomography (OCT) devices are non-contact instruments that can measure the depth of scars, other causes of cloudiness of the cornea, and degree of corneal thinning in patients with keratoconus. Laser Custom Corneal Collagen Cross-linking (CXL) significantly decreases corneal aberrations and improves vision. This study will use OCT-guided setting …

corneal thinning
optical coherence tomography
corneal collagen cross-linking
  • 01 Feb, 2022
  • 1 location
A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP (ROP3)

This randomized clinical trial will compare retinal outcomes with low-dose intravitreous bevacizumab (0.063 mg) versus laser photocoagulation as treatment for infants with type 1 retinopathy of prematurity (ROP). The study also will assess neurodevelopment, refractive error, visual acuity, and peripheral visual fields.

  • 05 Jun, 2022
  • 10 locations
A Multicenter Trial of Radiofrequency Ablation vs. Surgery as Treatment of Papillary Thyroid Microcarcinoma.

The treatment of Papillary Thyroid Microcarcinoma (PTMC) nowadays varies among physicians, surgeons and radiologist. The recently published articles show that the prognosis of PTMC by different means of treatment strategies tends to be good. But multicentered, randomized, parallel and prospective study is rare. RFA is the abbreviation of "Radiofrequency Ablation", …

  • 26 Jan, 2021
  • 3 locations
Can the SurgInfoBot Improve the Consent Process for Endoscopy? A Randomised Controlled Trial

Human-computer interactions or 'Chatbots' have been utilized in a variety of healthcare settings, including the promotion of positive healthcare behaviors, the deliverance of psychological therapy, and the performance of diagnostic tasks. Standard methods of consenting patients for procedures may not always result in patients being fully informed; a 2004 study …

Accepts healthy volunteers
  • 22 Dec, 2021
  • 1 location
Fractional CO2 Laser Treatment of Hypertrophic Scars

Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints. There are also often significant psychosocial elements with these scars that are especially significant in the vulnerable pediatric population and their parents. Current scar treatment modalities are limited. …

Accepts healthy volunteers
  • 17 Oct, 2021
  • 1 location
Elastic Compression Stockings and Varicose Veins Recurrence (ECOS-VVR)

Hypothesis. Regular using of Class 1 below-knee graduated compression stockings (RAL GZ 387 standard) compared to the absence of elastic compression will reduce the risk of clinically significant varicose veins recurrence at 12 months after endovenous thermal ablation of the great saphenous vein and elimination of varicose tributaries.

thermal ablation
radiofrequency ablation
  • 17 Mar, 2022
  • 3 locations