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Found 14 clinical trials
Effect of Preoperative Carbohydrate Loading on Post-operative Insulin Resistance After Donor Hepatectomy.

It's a randomized control trial to compare the effect of preoperative carbohydrate loading versus fasting on post operative insulin resistance after donor hepatectomy in terms of donor outcomes. Investigator will analyze the data and elucidate the value of post operative insulin resistance in reducing the occurrence of complications, length of …

Accepts healthy volunteers
  • 07 Apr, 2022
  • 1 location
Intérêt du Traitement de la fièvre Par Refroidissement Externe Pour la Survie Des Patients ventilés en Choc Septique

The best strategy for managing fever in patients with septic shock remains unknown. In a pilot study, the investigators showed that fever control at normothermia allowed a better control of shock and evolution of organ failures. In this second trial the investigators will conduct a multicentre, open-label, randomized controlled, superiority …

  • 20 Oct, 2022
Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes

intra-abdominal infection. According to the previous retrospective study, changes of serum lactate level on postoperative day1 could predict the incidence rate of postoperative intra-abdominal infection

  • 03 Oct, 2021
  • 1 location
Thiamine as a Metabolic Resuscitator After Cardiac Arrest (THACA)

This is a randomized, double-blind, placebo controlled study to investigate the effect of intravenous thiamine (vitamin B1) on lactate, cellular oxygen consumption, global oxygen consumption and biomarkers of neurologic injury after out-of-hospital cardiac arrest (OHCA). .

out-of-hospital cardiac arrests
  • 27 Feb, 2022
  • 1 location
Laser Therapy on Tension-type Cephalea and Orofacial Pain in Post-covid-19 Patients

Considering the auxiliary potential effect of photobiomodulation in controlling persistent CTT and TMD-related pain in patients who have been diagnosed with COVID-19, and are recovered from the viral infection, we intend to conduct a clinical trial comparing two modalities of therapeutic laser application: local application and transcutaneous application in the …

pain relieving
Accepts healthy volunteers
  • 08 Jul, 2022
  • 2 locations
Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Intensive care unit (ICU) mortality in patients with septic shock and acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) remains high and approximates 50-60%. Sepsis is the leading etiology for AKI and CRRT …

renal replacement therapy
  • 20 Aug, 2021
  • 1 location
Physical Restraint of Critically Ill Patients

Background: Physical restraint of patients in the intensive care unit (ICU) is a common practice, with estimated prevalence of 50% of all ICU patients, with and without invasive ventilation support(1). The prevalence of physical restraint varies between ICU's according to patient population (surgical, cardiac, trauma, burns and general intensive care …

  • 18 Sep, 2021
  • 1 location
Lower Silesia Cardiogenic Shock Initiative (LSCSI)

LSCSI is a Hub&Spoke project with the main aim to improve the outcome of patients with cardiogenic shock in Lower Silesia region, Poland. It consists of one "hub" which is Wroclaw University Hospital and eleven "spokes" which are eleven cardiology departments situated in Lower Silesian Voivodeship. The consortium have unified …

  • 04 Oct, 2022
  • 1 location
Prognostic Impact of Admission Glucose Level in Septic Patients Admitted to the Intensive Care Unit- a Retrospective Study

Background Sepsis is one of the most common reasons for admission to intensive care units (ICU) worldwide. About 30% of all patients admitted to intensive care suffer from sepsis (1). Sepsis causes an extreme physiological stress response, with significant changes in metabolism and disruption in glucose regulation. Disorder of glucose …

septic shock
  • 12 Oct, 2022
  • 1 location
Association of Postoperative Lactate Levels With Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Graft Surgery

measures. Lactate is the final product of anaerobic glycolysis. Serum lactate level are increased in case of inadequate oxygen delivery to tissues. The investigators aim to assess whether serum lactate

  • 27 Oct, 2022