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Found 19 clinical trials
Administration of Kisspeptin to Subjects With Reproductive Disorders

The investigators are seeking participants for a study of the role of kisspeptin in the reproductive system. Kisspeptin is a naturally occuring hormone in humans that stimulates the production of reproductive hormones. The investigators hypothesize that kisspeptin administration will be a useful tool for characterizing certain reproductive disorders.

prolactin
Accepts healthy volunteers
acne
testicular
estradiol
  • 808 views
  • 22 Jul, 2022
  • 1 location
Efficacy and Safety of Long Term Use of hCG or hCG Plus hMG in Males With Isolated Hypogonadotropic Hypogonadism (IHH) (IHH)

This study will evaluate the efficacy and safety of long term use of hCG alone or hCG plus hMG in the treatment of male patients with isolated hypogonadotropic hypogonadism (IHH). One third of

serum fsh level
testosterone
hormone levels
gonadotropin
pituitary hormones
  • 156 views
  • 04 Mar, 2022
  • 1 location
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate

The purpose of this study is to explore the genetic basis of reproductive disorders and cleft lip and/or palate.

cleft lip
Accepts healthy volunteers
hypogonadism
cleft lip/palate
klinefelter syndrome
  • 283 views
  • 10 Jul, 2022
  • 1 location
GROWing Up With Rare GENEtic Syndromes

GROWing Up With Rare GENEtic Syndromes: Introduction Rare complex syndromes Patients with complex genetic syndromes, by definition, have combined medical problems affecting multiple organ systems, and intellectual disability is often part of the syndrome. During childhood, patients with rare genetic syndromes receive multidisciplinary and specialized medical care; they usually receive …

genetic disorder
intellectual disability
premature
congenital disorders
diagnostic tests
  • 196 views
  • 09 Feb, 2021
  • 1 location
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers

Magnetic Resonance Imaging (MRI) unlike X-rays and CT-scans does not use radiation to create a picture. MRI use as the name implies, magnetism to create pictures with excellent anatomical resolution. Functional MRIs are diagnostic tests that allow doctors to not only view anatomy, but physiology and function. It is for …

asperger syndrome
psychiatric disorder
Accepts healthy volunteers
developmental disabilities
attention deficit disorder
  • 566 views
  • 22 Sep, 2022
  • 1 location
The Molecular Basis of Inherited Reproductive Disorders

Background During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. Some people have low hormone levels that severely delay or prevent puberty. Others start puberty abnormally early. Other people may have a normal puberty but develop reproductive disorders later …

early puberty
hormone levels
hypogonadism
hormones released
gonadotropin
  • 673 views
  • 17 Sep, 2022
  • 2 locations
Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype (EMKISCA)

Observational study of 160 patients with sex-chromosome abnormalities and 160 matched controls. Blood, fat, muscle, skin, buccal swaps, urine will be collected and analyzed for DNA, RNA and methylation patterns. The goal is to associated genotype and epigenetic changes with the phenotype of patients with sex-chromosome abnormalities. Patients participate in …

chromosomal disorder
Accepts healthy volunteers
chromosomal abnormality
  • 0 views
  • 08 Jul, 2022
  • 1 location
The Potential of Sperm Retrieved by Micro-TESE to Fertilize Vitrified/Warmed Oocytes

Couples referred for microdissection-TESE (m-TESE) due to Klinefelter's syndrome, maturation stop in the spermatogenesis, or failed retrieval of testicular spermatozoa by conventional techniques

  • 0 views
  • 08 Jun, 2022
  • 2 locations
The Role of Gonadotropin Pulsations in the Regulation of Puberty and Fertility

Background The body produces gonadotropin-releasing hormone (GnRH) about every 2 hours. GnRH travels through the bloodstream to the pituitary gland, where it stimulates the gland to produce hormones called gonadotropins. These hormones stimulate the testicles or ovaries. The testicles produce testosterone and develop sperm. The ovaries produce estrogen and prepare …

testosterone
hormone levels
hypogonadism
hypogonadotropic hypogonadism
gonadotropin
  • 1118 views
  • 14 Sep, 2022
  • 1 location