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Found 26 clinical trials
Examination of Idiopathic Hypogonadotropic Hypogonadism (IHH)and Kallmann Syndrome (KS)

The purpose of the study is to examine how Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism (IHH) affect reproductive hormones. These disorders are caused by a defect in

sex hormones
testosterone
idiopathic hypogonadotropic hypogonadism
pituitary
testosterone level
  • 85 views
  • 27 Jan, 2021
  • 1 location
A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism

Testosterone is the principal androgen produced by the male testes. Hypogonadism is the result of inadequate production of testosterone by the Leydig cells of the testes and is reflected by serum concentrations of testosterone of < 300 ng/dL, with no discernible diurnal pattern. The etiology of hypogonadism may be primary …

aveed injectable product
testosterone
hypogonadotropic hypogonadism
testim
testosterone level
  • 32 views
  • 03 Apr, 2021
  • 6 locations
Very Large Sizes in Adolescents : Tibial and Femoral EPIphysiodesis

The very large sizes can be very disabling and at the origin of a difficult psychological experience. Some families are in demand for a growth-curbing treatment. Currently, only hormonal treatments are offered in France but they are at the origin of many side effects. Northern European countries applied a surgical …

  • 0 views
  • 17 Mar, 2021
  • 5 locations
Hypogonadotropic Hypogonadism in Obese Young Males

Obesity can lead to low testosterone concentrations in young men. This study will study the effects of low testosterone in those men and the result of treating them with clomiphene.

testosterone
clomiphene
testosterone level
secondary hypogonadism
klinefelter syndrome
  • 63 views
  • 26 Jan, 2021
  • 1 location
Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism

The goal of this study is to develop novel treatments for patients with a condition called hypogonadotropic hypogonadism (HH) through the use of exogenous kisspeptin.

  • 0 views
  • 04 Mar, 2021
  • 1 location
Neuropeptides in Human Reproduction

The investigators are seeking healthy volunteers and volunteers with reproductive disorders for the study of the role of dynorphin in the reproductive system. Dynorphin is a naturally occurring opioid hormone that is blocked by naloxone. We hypothesize that naloxone, by blocking dynorphin, will stimulate production of GnRH and kisspeptin, 2 …

reproductive hormones
thyroid stimulating hormone
kisspeptin
body mass index
klinefelter syndrome
  • 98 views
  • 27 Jan, 2021
Kisspeptin in the Evaluation of Delayed Puberty

Some children with delayed puberty will eventually enter puberty on their own. However, some children with delayed puberty have a permanent condition and require medical treatment to undergo puberty. Right now, there is no reliable diagnostic tool to tell whether a child's delayed puberty will be self-resolving or permanent. The …

testosterone
testosterone level
insulin-like growth factor 1 (igf-1)
testicular
thyroid stimulating hormone
  • 23 views
  • 27 Jan, 2021
Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling

The investigators are looking for subjects to complete a study on the role of kisspeptin in the reproductive system. Kisspeptin is a naturally occurring hormone in humans that tells the body to produce other reproductive hormones. However, giving someone a continued amount of kisspeptin over a period of time can …

secondary hypogonadism
reproductive hormones
screening procedure
testicular
kisspeptin
  • 13 views
  • 28 Jan, 2021
  • 1 location
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism

The investigators have preliminary data suggesting that obese patients with hypogonadotropic hypogonadism (HHG) have minimal benefit from testosterone therapy likely because of its conversion to

behavior modification
testosterone level
estrogen
malnutrition
body mass index
  • 941 views
  • 30 Jan, 2021
  • 1 location
Baselines in Reproductive Disorders

> Hypothalamic Amenorrhea (HA) Idiopathic hypogonadotropic hypogonadism (IHH) Polycystic ovarian disease (PCOD) Acquired hypogonadotropic hypogonadism (AHH)

idiopathic hypogonadotropic hypogonadism
pituitary
polycystic ovarian syndrome
endocrine disorder
acquired hypogonadotropic hypogonadism
  • 170 views
  • 07 Nov, 2020
  • 1 location