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Found 9 clinical trials
Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling

The investigators are looking for subjects to complete a study on the role of kisspeptin in the reproductive system. Kisspeptin is a naturally occurring hormone in humans that tells the body to

estradiol
reproductive hormones
testicular
kisspeptin
klinefelter syndrome
  • 13 views
  • 08 Jul, 2021
  • 1 location
Kisspeptin Influence on Glucose Homeostasis

This study examines how a naturally occurring peptide called kisspeptin might regulate blood sugar and insulin levels.

insulin
hyperlipidemia
fasting
insulin resistance
osteoporosis
  • 26 views
  • 30 Jan, 2022
  • 1 location
Kisspeptin in the Evaluation of Delayed Puberty

puberty. Right now, there is no reliable diagnostic tool to tell whether a child's delayed puberty will be self-resolving or permanent. The hormone kisspeptin has the potential to prospectively diagnose

insulin
testicular
electrolytes
kisspeptin
insulin-like growth factor 1 (igf-1)
  • 23 views
  • 09 Jul, 2021
  • 1 location
Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism

The goal of this study is to develop novel treatments for patients with a condition called hypogonadotropic hypogonadism (HH) through the use of exogenous kisspeptin.

kisspeptin
secondary hypogonadism
klinefelter syndrome
  • 0 views
  • 22 Aug, 2021
  • 1 location
Administration of Kisspeptin to Subjects With Reproductive Disorders

The investigators are seeking participants for a study of the role of kisspeptin in the reproductive system. Kisspeptin is a naturally occuring hormone in humans that stimulates the production

testicular
acne
pituitary
Accepts healthy volunteers
kisspeptin
  • 808 views
  • 24 Jan, 2022
  • 1 location
Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test

The goal of this study is to understand how exogenous kisspeptin affects metabolism by evaluating responses to an oral glucose tolerance test

Accepts healthy volunteers
  • 0 views
  • 23 Nov, 2021
  • 1 location
Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Physiologic Mixed Meal Tolerance

This study utilizes infusions of kisspeptin in healthy women to isolate the impact of kisspeptin on beta-cell responsivity assessed by the mixed meal tolerance test.

chronic disease
illicit drugs
diabetes
body mass index
  • 0 views
  • 19 Jul, 2021
Neuropeptides in Human Reproduction

opioid hormone that is blocked by naloxone. We hypothesize that naloxone, by blocking dynorphin, will stimulate production of GnRH and kisspeptin, 2 other naturally occurring reproductive hormones

kisspeptin
hypogonadism
prolactin
screening procedure
gonadotropin
  • 98 views
  • 07 Jul, 2021
Opioid Antagonism in Hypogonadotropic Hypogonadism

The goal of this study is to evaluate the effects of opioid antagonists on the hypothalamic-pituitary-gonadal axis in subjects with idiopathic hypogonadotropic hypogonadism (HH).

idiopathic hypogonadotropic hypogonadism
pituitary
kisspeptin
klinefelter syndrome
secondary hypogonadism
  • 0 views
  • 01 Dec, 2021
  • 1 location