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Found 1436 clinical trials
Assess Safety, Tolerability and Pharmacokinetics of AntiBKV in Healthy Adult Volunteers. (SAFE KIDNEY I)

BK virus (BKV) is a member of the polyomavirus family with a prevalence of up to 90% in the general population. In immunocompromized individuals, such as kidney transplant recipients (KTRs) who receive immunosuppressant therapy to prevent graft rejection, BKV turns into an opportunistic pathogen. BK viremia has been reported to …

Accepts healthy volunteers
  • 0 views
  • 24 May, 2022
  • 1 location
Left Atrial Appendage Closure in Patients With Non-valvular Atrial Fibrillation and End-stage Chronic KIDNEY Disease (LAA-KIDNEY)

In the proposed event driven trial, LAA closure devices will be compared in a 1:1 randomization to best medical care in AF patients at high risk of stroke and bleeding with ESKD. The trial will allow the use of the CE marked and clinically used LAA device Amplatzer Cardiac Plug …

  • 0 views
  • 09 Jun, 2022
A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease (TWOPLUS-HD)

The optimal frequency of hemodialysis treatments in patients with incident end-stage kidney disease in not known. This pilot trial will randomize patients with incident end-stage kidney disease

Accepts healthy volunteers
chronic renal failure
chronic kidney disease
renal disease
  • 6 views
  • 07 Jul, 2022
  • 1 location
To Evaluate the Patient Tolerance Pharmacodynamics and Pharmacokinetics of Lanthanum Polystyrene Sulfonate Powder

The aim of the study is: To evaluate the tolerance of lanthanum polystyrene sulfonate powder in patients with end-stage renal disease (ESRD-HD) hyperphosphatemia with multiple doses and

fasting
renal disease
lanthanum carbonate
lanthanum carbonate 500 mg
chronic kidney disease
  • 2 views
  • 08 Aug, 2021
  • 1 location
A Phase 1 Study of SSS17 in Healthy Subjects.

This study will investigate the efficacy, safety, pharmacokinetics and pharmacodynamics of single oral administration of 5 mg, 15 mg, 20 mg and 25 mg of SSS17 compared with placebo, and evaluate the efficacy, safety, tolerance, pharmacokinetics and pharmacodynamics of multiple oral administration of 15 mg and 20 mg of SSS17 …

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Different Immunosuppressive Treatment in iMN

The primary objective of this study is to compare the 24 month remission of different immunosuppressive therapies in the treatment of idiopathic membranous nephropathy (iMN)

  • 0 views
  • 30 Apr, 2022
  • 1 location
An Exercise Facilitator to Activate Simple Training Programs in the Dialysis Center

Low physical activity levels and progressive poor functional capacity affect quality of life and clinical outcomes of Chronic Kidney Disease (CKD) patients. Interventions to prevent the

  • 0 views
  • 09 May, 2021
  • 1 location
Investigating the Efficacy and Safety of Roxadustat (FG-4592) for Treatment of Anemia in Pediatric Patients With CKD

This open-labeled, one-center study is designed to evaluate the efficacy and safety of roxadustat in ESA-nave and ESA-treated pediatric patients with CKD Stages 3, 4, and 5 who are receiving dialysis or not. The study will enroll patients between the ages of 2 to <18 years. Approximately 30 patients will …

  • 0 views
  • 17 Aug, 2021
  • 1 location
RandomizEd ClinicAL triaL on the Efficacy and saFety of Incremental Hemodialysis (REAL-LIFE)

Background: The thrice-weekly hemodialysis (HD) regimen is widely accepted as a standard prescription. The concept of incremental dialysis has been established as a possible alternative for patients with preserved diuresis and end-stage renal failure in need of HD. The main problems related to prescription of incremental HD are an arbitrary …

  • 0 views
  • 04 Jun, 2022
  • 1 location
The Home Blood Pressure (BP) Trial (Home-BP)

The main study will be a two arm 10-month, cross-over randomized controlled trial of 200 participants treated with end-stage-kidney-disease treated with in-center hemodialysis in the Seattle and

  • 0 views
  • 15 Jun, 2022
  • 2 locations