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Found 384 clinical trials
CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition (Cyto-KIK)

without any visible kidney cancer in their body at some point during the course of treatment.

cancer
nephrectomy
targeted therapy
nivolumab
neutrophil count
  • 42 views
  • 22 Apr, 2022
  • 2 locations
Study of Nivolumab in Combination With 177Lu-girentuximab for Kidney Cancer

The purpose of this study is to see if the combination of 177Lu-girentuximab and nivolumab is a safe and effective treatment for advanced clear cell renal cell carcinoma/ccRCC that has the CAIX protein.

systemic therapy
ct scan
clear cell renal cell carcinoma
nephrectomy
cancer
  • 0 views
  • 24 Mar, 2022
  • 5 locations
Modi-1 in Breast, Head and Neck, Ovarian, or Renal Cancer (ModiFY)

The main objectives of this study are to assess the safety, tolerability, immunological activity, and preliminary efficacy of the Modi-1/Modi-1v vaccine, both as monotherapy and in combination with a checkpoint inhibitor (CPI) such as pembrolizumab or nivolumab (where these are standard of care in a non-neoadjuvant setting), in patients with …

systemic therapy
chemoradiotherapy
measurable disease
cancer
nivolumab
  • 0 views
  • 01 May, 2022
  • 2 locations
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues

anticoagulants
cancer
neutrophil count
metastasis
glomerular filtration rate
  • 0 views
  • 22 Mar, 2022
  • 1 location
Individualized Treatment Strategy for Patients With Metastatic Non-clear Cell Renal Cell Carcinoma

The purpose of the open-label INDIGO-study is to examine whether a first line individualized treatment strategy based on DNA and RNA analyses from the patient's tumor is feasible. Moreover, to involve the patient further in their treatment via patient-reported outcomes (PRO) measurements in a value-based healthcare setup with simultaneous analyses …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Preliminary Evaluation of Uptake of [68Ga]P16-093 in Metastatic Prostate and Renal Cancer

An phase I study to evaluate the uptake of [68Ga]P16-093 in known or suspected metastatic prostate or renal cancer to establish the feasibility of using [68Ga]P16-093 to image PSMA expressing

pet/ct scan
MRI Scan
brachytherapy
cancer
prostatectomy
  • 72 views
  • 11 May, 2022
  • 1 location
DWI in the Diagnosis of Histological Types of Nephroblastoma in Children

Initially, or after preoperative chemotherapy, patients with a kidney tumor are examined on 3T MR scanner or 1.5T MR scanner. A standard MRI study of the abdomen with contrast enhancement is

  • 0 views
  • 02 Apr, 2021
  • 1 location
Nivolumab + Ipilimumab With Immunostimulatory Embolization for Stage 4 Renal Cell Carcinoma With Unresected Primary

This single center phase 1 trial will study the combination of nivolumab+ipilimumab with embolization in participants with renal cell carcinoma. The study will evaluate the safety of embolotherapy in patients with metastatic RCC receiving nivolumab+ipilimumab. The hypothesis is that the number of serious adverse events will be no greater than …

  • 0 views
  • 31 Jan, 2021
  • 1 location
Study of Nivolumab and Axitinib in Patients With Advanced Renal Cell Carcinoma

This is a Phase I/II, open-label, multi-center study of axitinib in combination with nivolumab in patients with previously treated and untreated advanced RCC. This clinical study will be composed of a dose finding phase (Phase I) and two parallel dose expansion phases (Phase II). The dose finding phase will assess …

systemic therapy
measurable disease
gilbert's syndrome
advanced renal cell carcinoma
tyrosine
  • 41 views
  • 25 Nov, 2021
  • 4 locations
Neo-adjuvant SABR for IVC Tumor Thrombus in Newly Diagnosed RCC

To evaluate the safety and feasibility of pre-operative SABR of RCC IVC tumor thrombus. To evaluate the effect of pre-operative SABR in RCC IVC tumor thrombus on relapse free survival at one year.

metastasis
kidney tumor
kidney cancer
cancer
nephrectomy
  • 8 views
  • 05 Jan, 2022
  • 1 location