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Found 370 clinical trials
Daratumumab in Treating Patients With Muscle Invasive Bladder Cancer or Metastatic Kidney Cancer

Objectives Primary Safety and tolerability of therapy with daratumumab in a cohort of patients with metastatic renal cell carcinoma and a cohort of patients with muscle invasive bladder cancer. Secondary 1A. To assess the proportion of patients who achieve pathological CR with daratumumab in patients with muscle invasive bladder cancer. …

metastasectomy
bladder cancer
potassium
invasive bladder cancer
cancer
  • 21 views
  • 22 Jan, 2021
  • 2 locations
Pazopanib Hydrochloride and Bevacizumab in Treating Patients With Previously Untreated Metastatic Kidney Cancer

This phase I/II trial studies the side effects and best dose of pazopanib hydrochloride and bevacizumab and to see how well they work in treating patients with previously untreated kidney cancer

24-hour urine protein
cancer
solid tumour
bevacizumab
pazopanib
  • 114 views
  • 25 Jan, 2021
  • 4 locations
CBM588 Nivolumab and Ipilimumab in Treating Patients With Stage IV or Advanced Kidney Cancer

This phase I trial studies how well CBM588 works when given together with nivolumab and ipilimumab in treating patients with kidney cancer that is stage IV or has spread to other places in the

ipilimumab
cancer
liver metastasis
solid tumour
neutrophil count
  • 38 views
  • 26 Jan, 2021
  • 1 location
Preventing Toxicity in Renal Cancer Patients Treated With Immunotherapy Using Fecal Microbiota Transplantation

Cancer immunotherapy has been largely adopted in oncology patient management in the last decade. The deep and long responses to immunotherapy have accelerated the approval of these drugs across multiple disease sites. However, these agents can also be toxic to patients, meaning, the patient will have to discontinue treatment and …

carcinoma
ipilimumab
cancer
kidney cancer
curative surgery
  • 21 views
  • 25 Jan, 2021
  • 1 location
MRI-Guided Radiation Therapy for the Treatment of Early-Stage Kidney Cancer the MRI-MARK Trial

This phase II trial investigates how well MRI-guided stereotactic body radiation therapy works in treating patients with early-stage kidney cancer. Radiation therapy uses high energy radiation

kidney cancer
carcinoma
tumor cells
cancer
  • 0 views
  • 08 Apr, 2021
3D-biomodels for Surgical Planning in Patients With Renal Cancer and Vascular Involvement

Objectives Apply 3D- printed biomodels in patients with renal cancer (RCa) and vascular involvement (VTT) to: (1) improve surgical planning, (2) upgrade surgical

  • 0 views
  • 01 Feb, 2021
  • 2 locations
CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition

without any visible kidney cancer in their body at some point during the course of treatment.

pet scan
carcinoma
targeted therapy
cancer
kidney cancer
  • 0 views
  • 25 Jan, 2021
Talazoparib and Axitinib for People With Previously Treated Advanced Kidney Cancer

Researchers are doing this study to find out if the combination of the drugs axitinib and talazoparib is a safe and effective treatment for people with your previously treated advanced kidney

line of therapy
cancer
liver metastasis
hysterectomy
renal function
  • 7 views
  • 29 Jan, 2021
  • 7 locations
Individualized Treatment Strategy for Patients With Metastatic Non-clear Cell Renal Cell Carcinoma

The purpose of the open-label INDIGO-study is to examine whether a first line individualized treatment strategy based on DNA and RNA analyses from the patient's tumor is feasible. Moreover, to involve the patient further in their treatment via patient-reported outcomes (PRO) measurements in a value-based healthcare setup with simultaneous analyses …

  • 0 views
  • 27 Jan, 2021
  • 1 location
DWI in the Diagnosis of Histological Types of Nephroblastoma in Children

Initially, or after preoperative chemotherapy, patients with a kidney tumor are examined on 3T MR scanner or 1.5T MR scanner. A standard MRI study of the abdomen with contrast enhancement is

  • 0 views
  • 02 Apr, 2021
  • 1 location