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Found 375 clinical trials
First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours

The purpose of this study is to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Antitumor Activity of AZD8701 Alone and in Combination with Durvalumab (MEDI4736) in Adult Subjects with Select Advanced Solid Tumors

breast cancer
solid tumour
progressive disease
monoclonal antibodies
small lung
  • 50 views
  • 11 Apr, 2021
  • 8 locations
MR/TRUS Fusion Guided Prostate Biopsy

This study will determine if targeted (Magnetic Resonance (MR) / Ultrasound (US) fusion biopsy) plus conventional biopsy is superior to conventional biopsy alone in diagnosing subjects with prostate cancer.

prostate biopsy
anesthesia
cancer
transrectal ultrasound
MRI
  • 1 views
  • 23 Jan, 2021
  • 1 location
Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Background People with von Hippel-Lindau (VHL) can have problems with a variety of organs, such as the pancreas. The disease can cause tumors of the pancreas. This can result in life-threatening complications. Researchers want to learn more about these pancreatic tumors and how to better detect them. This may help …

cyst
pet/ct scan
neuroendocrine tumor
genetic testing
ct scan
  • 0 views
  • 21 Mar, 2021
  • 1 location
SABR for Renal Tumors

Renal Cell Carcinoma (RCC) is the most common type of kidney cancer. The usual treatment for this type of cancer is surgery. Considering the most common patients are an average age of 65 and

metastasis
cancer
renal neoplasm
kidney cancer
carcinoma
  • 13 views
  • 23 Jan, 2021
  • 1 location
Irreversible Electroporation(IRE) For Unresectable Renal Tumors

The purpose of this study is to investigate the safety and efficacy of irreversible electroporation (IRE) for unresectable renal tumors.

renal neoplasm
  • 8 views
  • 24 Jan, 2021
  • 1 location
Multiparametric MRI for Diagnosing Small Renal Tumors

differentiate benign from malignant renal tumors. The originality of this project lies in the opportunity to simultaneously assess the performance of mpMRI in diagnosing renal tumors in a routine clinical

  • 0 views
  • 28 Jan, 2021
  • 16 locations
Neoadjuvant Cabozantinib in Treating Patients With Locally Advanced Kidney Cancer

This phase II clinical trial studies how well cabozantinib works in treating patients with kidney cancer before surgery. Cabozantinib may stop the growth of tumor cells by blocking some of the

bone metastases
gilbert's syndrome
hormone therapy
cabozantinib
ovarian suppression
  • 5 views
  • 26 Jan, 2021
  • 1 location
Pencil Beam Scanning in Patients With Renal Tumors

This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.

anaplasia
renal neoplasm
beam radiation
nephroblastoma
sarcoma
  • 15 views
  • 28 Jan, 2021
  • 1 location
Percutaneous Cryoablation Versus Partial Nephrectomy for T1b Renal Tumor

The aim of our study is to assess the long-term oncological and functional outcomes of cryoablation for T1b renal tumors, as well as such important parameters as the patient's quality of life

renal neoplasm
nephrectomy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Contrast-Enhanced Ultrasound for Kidney Cancer Subtyping and Staging

The purpose of this study is to determine if contrast-enhanced ultrasound can detect abnormal features of kidney lesions in patients with suspected kidney cancer with the same accuracy as

nephrectomy
cancer
  • 1 views
  • 04 Feb, 2021
  • 1 location