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Found 387 clinical trials
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Onco-primary Care Networking to Support TEAM-based Care

The proposed ONE TEAM Study is an 18-month, cluster randomized controlled trial. This study will use a sequential multiple assignment randomized trial (SMART) design with a second randomization for the intervention group using a dynamic treatment regimen approach. The investigators propose to randomize 800 adults with newly-diagnosed selected cancers treated …

hypertension
cardiovascular complications
primary cancer
chronic disease
a 12
  • 0 views
  • 04 Oct, 2021
  • 1 location
None
Efficacy of Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors

This is an open-label, single arm, non-randomized, multicenter phase II study to evaluate the efficacy of spartalizumab in monotherapy in metastatic patients with Programmed Death-1 (PD1)-high-expressing tumors.

measurable disease
alopecia
cancer
  • 0 views
  • 22 Aug, 2021
  • 10 locations
None
Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes

This study examines at-home monitoring of patient-generated phsyiologic health data and patient-reported outcomes. Patient-generated health data using at-home monitoring devices and smart device applications are used more and more to measure value and quality in cancer care. This trial may show whether at-home monitoring programs can improve the care of …

primary cancer
cancer treatment
cancer
cancer care
  • 0 views
  • 22 Aug, 2021
  • 2 locations
None
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures …

other disease
rare diseases
  • 4 views
  • 08 Sep, 2021
  • 2 locations
None
Liquid Biopsy in Hepatocellular Carcinoma

Circulating tumor DNA (ctDNA) carrying tumor-specific sequence alterations has been found in the cell-free fraction of blood. Hepatocellular carcinoma (HCC) specimens are difficult to obtain, and noninvasive methods are required to assess cancer progression and characterize underlying genomic features. Use of 'liquid biopsy' by assessing circulating cell free DNA enables …

  • 0 views
  • 05 Oct, 2021
  • 1 location
None
Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue

Background Urothelial cancer is cancer of the bladder, ureter, and urethra. Researchers want to better understand what changes in a person s cells and genes cause this cancer to form. This may help them find new ways to treat it. Objective To perform DNA sequencing to help researchers learn the …

urine test
Accepts healthy volunteers
bladder cancer
bladder tumor
cancer
  • 30 views
  • 24 Oct, 2021
  • 1 location
None
Evaluation of Clinical Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

The aim of this study is the characterization from epidemiological, radiomics and molecular point of view of lung metastasis of patients at beginning affected by pancreatic adenocarcinoma (PDAC), which after the resection of primitive tumor have met with initial recurrence of the disease exclusively at the lung level.

pdac
metastasis
  • 0 views
  • 24 Jan, 2021
  • 4 locations