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Found 370 clinical trials
DWI in the Diagnosis of Histological Types of Nephroblastoma in Children

Initially, or after preoperative chemotherapy, patients with a kidney tumor are examined on 3T MR scanner or 1.5T MR scanner. A standard MRI study of the abdomen with contrast enhancement is

  • 0 views
  • 02 Apr, 2021
  • 1 location
Nivolumab + Ipilimumab With Immunostimulatory Embolization for Stage 4 Renal Cell Carcinoma With Unresected Primary

This single center phase 1 trial will study the combination of nivolumab+ipilimumab with embolization in participants with renal cell carcinoma. The study will evaluate the safety of embolotherapy in patients with metastatic RCC receiving nivolumab+ipilimumab. The hypothesis is that the number of serious adverse events will be no greater than …

  • 0 views
  • 31 Jan, 2021
  • 1 location
A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma

CyberKnife Based Radiosurgery is a way to deliver large doses of radiation very accurately to a tumor. The ability of this technology to minimize radiation dose to organs adjacent to the target tumor allows a high dose to be delivered to the tumor, thus potentially increasing the efficacy of radiation …

cancer
ct scan
metastasis
brain metastasis
lung cancer
  • 40 views
  • 23 Jan, 2021
Combined Alternating Sunitinib and Bevacizumab (Avastin ) in Advanced Renal Cell Carcinoma (CASA)

Combined sunitinib and bevacizumab in advanced renal cell carcinoma.

primary tumor
advanced renal cell carcinoma
measurable disease
bevacizumab
monoclonal antibodies
  • 39 views
  • 22 Jan, 2021
  • 1 location
Post Marketing Surveillance for PROSENSE a Cryotherapy Treatment of Renal Cell Carcinoma

This experiment is designed for post marketing data collection of a cryosurgical system [PROSENSE of IceCure Medical], for the treatment of renal cell carcinoma (RCC).

carcinoma
  • 45 views
  • 25 Jan, 2021
  • 2 locations
Neo-adjuvant SABR for IVC Tumor Thrombus in Newly Diagnosed RCC

To evaluate the safety and feasibility of pre-operative SABR of RCC IVC tumor thrombus. To evaluate the effect of pre-operative SABR in RCC IVC tumor thrombus on relapse free survival at one year.

kidney cancer
cancer
tubal ligation
metastasis
nephrectomy
  • 8 views
  • 16 Mar, 2021
  • 1 location
Study of TAK-228 In Patients With Previously Treated Metastatic Renal Cell Carcinoma

This research study is investigating a drug as a possible treatment for metastatic renal cell carcinoma. The intervention involved in this study is TAK-228.

liver metastasis
measurable disease
cancer
metastasis
nephrectomy
  • 280 views
  • 27 Jan, 2021
  • 7 locations
Nivolumab in Combination With Ipilimumab in Patients With Metastatic Renal Cell Carcinoma

Immunotherapy with checkpoint inhibitors that target PD-1 and CTLA-4 have shown activity in mRCC. However, the optimal schedule of the combination therapy has yet to be defined. The objective of the trial is to determine the efficacy of combination immunotherapy of nivolumab and ipilimumab in patients with metastatic renal cell …

systemic therapy
measurable disease
nivolumab
platelet count
ipilimumab
  • 83 views
  • 14 Apr, 2021
  • 20 locations
Study of High Dose Interleukin-2 (IL-2) and Stereotactic Body Radiation (SBRT) in Patients With Metastatic Renal Cancer

All patients will receive IL-2 (14 planned doses with an additional cycle 14 days after the first). Responding patients with regressing disease are eligible for up to 6 IL-2 cycles. Patients assigned to SBRT arm will receive two doses of SBRT on the Wednesday and Friday before the Monday on …

kidney cancer
interleukin 2
cancer
interleukins
interleukin-2
  • 69 views
  • 23 Jan, 2021
  • 1 location
Study of Nivolumab and Axitinib in Patients With Advanced Renal Cell Carcinoma

This is a Phase I/II, open-label, multi-center study of axitinib in combination with nivolumab in patients with previously treated and untreated advanced RCC. This clinical study will be composed of a dose finding phase (Phase I) and two parallel dose expansion phases (Phase II). The dose finding phase will assess …

systemic therapy
advanced renal cell carcinoma
measurable disease
nivolumab
ipilimumab
  • 40 views
  • 30 Jan, 2021
  • 4 locations