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Found 8 clinical trials
HYPofractionated Adjuvant RadioTherapy in 1 Versus 2 Weeks in High-risk Patients With Breast Cancer (HYPART).

We at PGIMER have been practicing hypofractionated radiotherapy in breast cancer patients for the last 4 decades. Our standard doses have been 35Gy/15/3wks to the chest wall after mastectomy and 40Gy/16/3wks after breast conserving surgery (BCS).It is also a routine practice in the UK and in a few centers in …

invasive carcinoma
mastectomy
adjuvant chemotherapy
hormone therapy
breast-conserving surgery
  • 0 views
  • 01 Jul, 2021
  • 1 location
The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function (MAVHS)

Black individuals are at increased cardiovascular disease risk. The central goal of the study is to determine if mitochondrial reactive oxygen species influence blood vessel function and nervous system regulation of blood pressure differentially in black, compared to white individuals. These findings may help to explain a potential mechanism that …

Accepts healthy volunteers
diabetes
hypertension
cardiovascular disease
metabolic disorders
  • 55 views
  • 07 Oct, 2022
  • 1 location
A Pharmacological Trial With Sativex® and Gentamicin for Optimized Phamacological Treatment of Older Patients With Focus on Appetite Stimulation and Renal Risk Drugs (CanPan)

Malnutrition and inappropriate prescribing of renally excreted drugs are common among older persons and are associated with severe consequences such as complicated courses of treatment, mortality, and reduced quality of life. The overall purpose of CanPan is to optimize treatment of older persons with malnutrition with a focus on appetite …

  • 0 views
  • 16 Oct, 2022
Angiotensin 1-7 as a Therapy in the Treatment of COVID-19

Phase 2 ,double blind, randomized study of therapy with Angiotensin 1-7 in COVID-19 patients. 120 confirmed SARS-CoV-2 infected patients who exhibit moderate- clinical symptoms including dyspnea, cough and fever, hospitalized in the KETER department in several hospitals in Israel, will be enrolled. 60 patients will receive Ang 1-7 subcutaneously 500 …

  • 0 views
  • 30 Jan, 2021
  • 1 location
Infliximab and Adalimumab in Irritable Bowel Disease Patients.

This study aims to assess trough, TREM-1 levels and efficacy of IFX and ADA in IBD patients.

infliximab
colitis
enteropathy
adalimumab
  • 0 views
  • 12 Apr, 2022
Comparison of Fibrinogen Concentrate and Cryoprecipitate in Pediatric Cardiac Surgery Patients

The aim of the current pilot study proposal is to compare the use of the purified human fibrinogen concentrate (Fibryga, Octapharma USA) to cryoprecipitate for the treatment of cardiopulmonary bypass (CPB)-associated bleeding in pediatric cardiac patients in whom fibrinogen supplementation is indicated. The investigators' hypothesis is that fibrinogen concentrate will …

haemostasis
cryoprecipitate
cardiopulmonary bypass
fibrinogen
  • 0 views
  • 03 Nov, 2021
  • 1 location
The Natural History of Coronavirus Disease (COVID-19) in Systemic Autoimmune Diseases; An Observational Prospective Study

of the body. For the scan, they will have a radioactive substance injected into their arm through an IV. Kidney function tests Non-invasive vascular studies test. These tests are

Accepts healthy volunteers
  • 0 views
  • 22 Oct, 2022
  • 1 location
Sleep and Insulin Resistance: The Impact of Gender Affirming Hormone Therapy in the Adolescent Transgender Population (ATP)

Disordered sleep is a health issue with significant impacts on physical and psychological well-being that has increased in prevalence, but its impact on transgender adolescents has not been fully quantified. While there is found to be an impact of sex steroids on sleep, and sex-dependent differences in the impact of …

Accepts healthy volunteers
  • 0 views
  • 24 Oct, 2022
  • 1 location