Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 26 clinical trials
Non-Myeloablative Allogeneic Transplantation From Unrelated Donors in Multiple Myeloma

The protocol aims at reducing transplant toxicity and mortality in patients with multiple myeloma.

cell transplantation
  • 4 views
  • 07 Nov, 2020
  • 1 location
Clinical Study on the Treatment of Recurrent Glioblastoma With Anlotinib

Anlotinib is a novel small molecule multi-target tyrosine kinase inhibitor that can inhibit tumor angiogenesis and inhibit tumor cell growth. We performed second-generation gene sequencing on pathological specimens and cerebrospinal fluid of patients with recurrent glioblastoma.If patients have a genetic mutation VEGFRKitPDGFRFGFRand meet other eligibility criteria, they will be treated …

neutrophil count
glioblastoma multiforme
karnofsky performance status
measurable disease
corticosteroids
  • 0 views
  • 23 Jan, 2021
  • 1 location
Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia

The purpose of this study is to determine the safety and dosing of drug Sotatercept, as a subcutaneous injection, to stimulate production of red blood cell production. To be given every 28 days for up to four doses.

  • 31 views
  • 14 Mar, 2021
  • 1 location
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)

years, Karnofsky Performance Status (KPS) 70, life expectancy > 3 months, histological confirmation of primary tumor, with controlled or controllable extracranial disease, baseline Montreal

  • 0 views
  • 25 May, 2021
  • 4 locations
Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases

This trial is a pilot, Phase 2, sequential two-cohort study designed to test two de-escalated whole brain radiation therapy (WBRT) dose levels and assess their ability to maintain acceptable in-brain distant control. The WBRT dose would decrease as the study moves forward, both in terms of absolute value and equivalent …

whole-brain radiotherapy
solid tumor
metastasis
  • 20 views
  • 22 Mar, 2021
  • 3 locations
HAI Via Interventionally Implanted Port Catheter Systems

Procedures to provide interventional implantation of a port catheter system into the hepatic artery and adjacent regional chemotherapy of the liver are optimized in the scope of an open, single-arm trial in patients with metastases and cancers confined to the liver. The primary objective is the improvement of indication, implantation …

cancer
fluorouracil
metastasis
  • 51 views
  • 07 Nov, 2020
  • 2 locations
L-DOS47 Plus Doxorubicin in Advanced Pancreatic Cancer

This study will evaluate the safety and tolerability of escalating doses of L-DOS47 in combination with doxorubicin, as well as preliminary anti-tumor activity in patients with previously treated advanced pancreatic cancer.

karnofsky performance status
platelet count
metastasis
liver metastasis
thromboplastin
  • 0 views
  • 22 Apr, 2021
  • 3 locations
Front Line Ibrutinib for Newly Diagnosed Chronic Graft-Versus Host Disease

Background Chronic Graft Versus Host Disease (cGVHD) can occur after a person has had a stem cell or bone marrow transplant. In cGVHD, the donor cells attack the recipient s body. Researchers want to see if a drug called ibruntinib can block one of the proteins that lead to the …

immunosuppressive agents
neutrophil count
ibrutinib
budesonide
acute graft-versus-host disease
  • 0 views
  • 24 May, 2021
  • 2 locations
Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome

Brain tumor surgery is commonly associated with different degrees of preoperative intracranial hypertension and surrounding tumor edema, elicited by tumor underlying pathophysiology. During craniotomy for brain tumor resection maintenance of hemodynamic stability and intracranial homoeostasis is of paramount importance. Disordered hemodynamics or adverse stress may activate the immune inflammation or …

mediators
nervous
anesthesia
tumour resection
asa-ps
  • 37 views
  • 24 Jan, 2021
  • 1 location
Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.

Cancer-associated anorexia-cachexia is an insidious syndrome that has a major impact on the patient's quality of life, but is also associated with a significant reduction in survival. Despite its clinical importance, it remains a widely underestimated and untreated condition. Considering the scarcity of pharmacological measures, it is necessary to invest …

cancer
palliative care
megestrol
mirtazapine
anorexia
  • 0 views
  • 24 Jan, 2021
  • 1 location