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Found 29 clinical trials
Pomalidomide Treatment in Patients With Kaposi Sarcoma

This phase II trial studies the effect of pomalidomide in treating patients with Kaposi sarcoma. Pomalidomide is a cancer fighting drug that stops the growth of blood vessels, stimulates the

  • 0 views
  • 27 Jul, 2022
  • 2 locations
Nivolumab and Ipilimumab in Classical Kaposi Sarcoma (CKS)

A Phase 2 study of nivolumab plus ipilimumab in previously treated classical Kaposi Sarcoma (CKS)

  • 0 views
  • 22 Jan, 2021
  • 1 location
sEphB4-HSA in Treating Patients With Kaposi Sarcoma

This phase II trial studies recombinant EphB4-HSA fusion protein (EphB4-HSA) in treating patients with Kaposi sarcoma. Recombinant EphB4-HSA fusion protein may block the growth of blood vessels

  • 0 views
  • 09 Jul, 2022
  • 9 locations
Mirasol Evaluation of Reduction in Infections Trial (MERIT)

This is a prospective, randomized, double-blind, controlled study to determine the effectiveness of Mirasol-treated fresh whole blood (FWB) versus Standard-issue FWB for preventing transmission of transfusion-transmitted infections (TTIs). The incidence of pre-defined viral, bacterial, or parasitic TTIs in previously negative participants will be assessed by changes in laboratory findings at …

  • 3 views
  • 18 Feb, 2022
  • 1 location
Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated Tuberculosis (NEW-STRAT TB)

The New Strat-TB trial is a superiority Phase III randomised control clinical trial with a 2X2 factorial design. The main aim of the study is to assess the efficacy and safety of high dose rifampicin and levofloxacin for 14 days in addition to standard TB therapy with or without steroids …

  • 0 views
  • 23 Apr, 2022
Phase II Multicenter Study of Talimogene Laherparepvec in Classic or Endemic Kaposi Sarcoma (KAPVEC)

Kaposi Sarcoma (KS) is a lymphangioproliferation associated with human herpes virus 8 (HHV8) promoted by immunosuppression. HIV-related KS and iatrogenic posttransplantation KS are treated by

cancer chemotherapy
herpes
measurable disease
serum total bilirubin
systemic therapy
  • 0 views
  • 30 Jun, 2022
  • 1 location
Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Background Kaposi Sarcoma (KS) is common in people with human immunodeficiency virus (HIV) but can also occur in people who do not have HIV. KS tumors usually

atazanavir
AIDS
cytotoxic chemotherapy
measurable disease
systemic therapy
  • 0 views
  • 25 Jul, 2022
  • 1 location
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Background Kaposi sarcoma (KS) tumors grow on the skin, lymph nodes, lungs, bone, and gastrointestinal tract. KS often affects people with immune deficiencies

cancer chemotherapy
atazanavir
AIDS
cytotoxic chemotherapy
measurable disease
  • 12 views
  • 22 Jul, 2022
  • 1 location
Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

Background Kaposi sarcoma (KS) is a cancer most often seen in people with HIV. It causes lesions. These are usually on the skin but sometimes in the lymph nodes

antiretroviral agents
atazanavir
AIDS
measurable disease
systemic chemotherapy
  • 11 views
  • 25 Jul, 2022
  • 1 location
NT-I7 for Kaposi Sarcoma in Patients With or Without HIV

This phase I trial studies the best dose and effects of NT-I7 in treating Kaposi sarcoma in patients with or without HIV. NT-I7 works by using a patient's immune system to fight cancer. It is

wbc count
AIDS
hepatitis
HIV Vaccine
immunodeficiency
  • 0 views
  • 20 Jul, 2022
  • 3 locations