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Found 49 clinical trials
Melatonin Use After Primary Total Joint Arthroplasty

The purpose of this study is to determine the effect of melatonin supplementation on patient sleep quality, length of stay, and opioid consumption following primary, unilateral, elective total hip or knee arthroplasty.

  • 0 views
  • 10 Mar, 2022
  • 1 location
Microbial Growth in Operative Splash Basins During Total Joint Arthroplasty

than culturing surgical instruments. The objective of this study is to compare the microbial contamination rate of total joint arthroplasty instruments that have been placed in surgical splash

  • 4 views
  • 25 Mar, 2022
  • 1 location
Cost-effectiveness Evaluation of One Stage Versus Two Stage Exchange for Chronically Infected Total Hip and Total Knee Prostheses (IPRO)

Chronic infection after total joint arthroplasty generally requires implant exchange. Two stage exchange is considered as the gold standard procedure. However, some authors suggest that one

  • 0 views
  • 03 Mar, 2022
  • 1 location
Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty

This is a prospective, randomized, controlled, open label, parallel four-arm design, multi-center study to compare different intraoperative interventions in the prevention of acute PJI development.

avascular necrosis
joint reconstruction
  • 52 views
  • 13 Mar, 2022
  • 9 locations
Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications

Vitamin D status has been shown to have an effect on post-operative outcomes in total joint arthroplasty. The goal of this study is to determine if pre-operative supplementation and correction

joint arthroplasty
malnutrition
postoperative complications
cholecalciferol
vitamins
  • 0 views
  • 13 Mar, 2022
Optimal Dosing For Low-Dose Aspirin Chemoprophylaxis For VTE Following Total Joint Arthroplasty

This research study is attempting to answer the question of whether 81 mg aspirin once daily is as effective as 81 mg aspirin twice daily in preventing blood clots after total joint replacement surgery.

clot
aspirin
blood clot
total knee replacement
  • 0 views
  • 07 Apr, 2022
  • 1 location
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.

diabetes
Accepts healthy volunteers
body mass index
antibiotics
  • 5 views
  • 24 Mar, 2022
  • 1 location
Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial

The Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty (TKA): Multi-Center Trial is a study that will compare the effectiveness of various perioperative strategies for antibiotic delivery as prophylaxis for periprosthetic joint infections (PJI) and surgical site infection in elective primary TKA. The investigators hypothesize that a single dose …

inflammatory arthritis
cefazolin
osteoarthritis
total knee replacement
  • 177 views
  • 30 Apr, 2022
  • 11 locations
Total Joint Arthroplasty and Sleep

To compare non-prescription sleep aids (low-dose diphenhydramine and melatonin) to sleep hygiene education for improving postoperative sleep quality after total joint arthroplasty.

  • 1 views
  • 28 Feb, 2022
  • 1 location
Knotless Suture in Revision Total Joint Arthroplasty

Barbed suture has been demonstrated to be safe in primary hip and knee surgery and retrospective data suggests barbed suture represents no increased complications in the revision setting. Barbed suture may represent a faster, more effective way to perform revision arthroplasty closures. There are no Level I studies comparing traditional …

  • 0 views
  • 25 Mar, 2022
  • 1 location