Found 15 clinical trials
Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis
of O. volvulus microfilaria in skin, the parasite that causes river blindness. Secondary purposes are to determine the effectiveness of moxidectin compared to ivermectin once or twice a year
- 0 views
- 07 Oct, 2022
- 1 location
Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas
The purpose of this phase 3b study is to determine the safety of a single dose of moxidectin, compared to a single dose of ivermectin, in individuals living in an onchocerciasis endemic area.
- 0 views
- 07 Oct, 2022
- 1 location
Evaluation of Effectiveness of ALBENDAZOLIVERMECTIN Coformulation vs ALBENDAZOLE for Treatment of Intestinal Worms (ALIVE)
The purpose of this clinical trial is to evaluate a fixed-dose co-formulation (FDC) of ivermectin and albendazole for the treatment of all Soil Transmitted helminths (STH). The current strategy
- 6 views
- 15 Mar, 2022
- 1 location
Emodepside Phase II Trial for Treatment of Onchocerciasis
The trial evaluates safety, tolerability, pharmacodynamics, pharmacokinetics, dose-response, and efficacy of emodepside tablets, administrated as a range of dose regimens, in adults infected with Onchocerca Volvulus.
- 0 views
- 26 Mar, 2022
- 1 location
Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection
. Participants in Part 2 will most effective treatment combination determined in Part 1 for 14 days followed by ivermectin or matching placebo capsules at Month 6. Duration of treatment is 24 months.
- 0 views
- 15 Jun, 2022
- 2 locations
Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin)
Permethrin 5 % cream (repeated topical administration on two consecutive days), (ii) an add-on-combination consisting of escalated therapy with Permethrin 5 % cream and Ivermectin p.o. or (iii) an escalated
- 0 views
- 05 Sep, 2021
- 8 locations
Adjunctive Ivermectin Mass Drug Administration for Malaria Control (MATAMAL)
This is a cluster-randomized placebo-controlled clinical trial to evaluate the additive benefit of Ivermectin (IVM) (or Placebo) mass drug administration (MDA) to dihydroartemisinin-piperaquine
- 0 views
- 15 Mar, 2022
Field Studies on the Feasibility of Interrupting the Transmission of Soil-transmitted Helminths (STH)
many lymphatic filariasis (LF) programs have successfully treated entire populations with albendazole (in combination with ivermectin or diethylcarbamazine) and are transitioning to a state of post-MDA
- 68 views
- 01 Mar, 2022
- 3 locations
Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)
The trial will develop and validate a platform for quantitative assessment of antiviral effects in low-risk patients with high viral burdens and uncomplicated COVID-19 to determine in-vivo antiviral activity. In this randomized open label, controlled, group sequential adaptive platform trial, we will assess the performance of three distinct types of …
- 0 views
- 07 Oct, 2022
- 2 locations
The Efficacy of Ivermectin in Larger Doses in COVID-19 Treatment
Efficacy of Ivermectin in larger doses in COVID-19 treatment
- 187 views
- 21 Mar, 2021
- 1 location
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