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Found 849 clinical trials
Optimized Antiplatelet Therapy on the Prognosis of ACS Patients With Non-predominant Coronary Artery Disease After PCI

The study is to evaluate the effect of optimized 12-month step-down antiplatelet therapy (APT) compared with standard 12-month dual antiplatelet therapy in clinical net adverse events, cardiovascular and cerebrovascular adverse events and reducing clinical related bleeding events in the patients with acute coronary syndrome (ACS) who are not the predominant …

ticagrelor
stemi
unstable angina
aspirin
infarct
  • 0 views
  • 24 Jan, 2021
  • 1 location
Optimal Antithrombotic Therapy for ACS Patients Concomitant With AF and Implanted With New-generation DES (OPTIMA-3, 4)

It is a multi-center randomized clinical trial (RCT) which will enroll 3746 patients with acute coronary syndrome (ACS) concomitant non-valvular atrial fibrillation (NVAF) and undergoing new generation drug eluting stent (DES) implantation at 70 centers nationwide in China and contains two sub-studies. In the OPTIMA-3 sub-study, 2274 subjects who choose …

ticagrelor
aspirin
thrombosis
infarct
myocardial infarction
  • 51 views
  • 03 May, 2022
  • 1 location
ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO (ISCHEMIA-CTO)

Study design Prospective randomized open labeled multicenter study Hypotheses In asymptomatic patients with ≥ 10% of myocardial ischemia: PCI (Percutaneous Coronary

medical therapy
coronary artery disease
heart failure
stemi
heart disease
  • 56 views
  • 22 Mar, 2022
  • 15 locations
Prospective Evaluation of New Techniques in Radiation Reduction for Cardiovascular Computed Tomographic Angiography

Title: Evaluating New Radiation Techniques for Cardiovascular Imaging Background Imaging studies such as computed tomography (CT) scans involve the use of radiation to create the pictures. Heart and blood vessel CT scans can cause high radiation exposure. Different methods of creating CT pictures have been developed to reduce the radiation …

stenosis
coronary artery stenosis
computed tomography angiography
angiography
coronary ct
  • 0 views
  • 20 Oct, 2022
  • 1 location
Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial (PERFUSERCT)

The purpose of this study is to evaluate safety and effectiveness of CTP(computed tomography perfusion) guided revascularization vs FFR(Fractional flow reserve) guided revascularization

stenosis
angina pectoris
ct scan
  • 0 views
  • 04 Oct, 2022
  • 8 locations
An Open-label, Single-dose, Safety and Pharmacokinetic Study of Regadenoson in Pediatric Patients (Rapiscan PIP)

This is a multi-centre, open-label, single-dose safety, tolerability and PK-pharmacodynamics (PD) study of the vasodilator regadenoson in 3 paediatric age groups for whom a pharmacologic stress perfusion CMR test is clinically indicated; adolescents aged 12 to <18 years (Cohort A), children aged 2 to <12 years (Cohort B), and infants …

vasodilator
regadenoson
  • 0 views
  • 20 Oct, 2022
  • 4 locations
DyeVert System and Contrast-induced Acute Kidney Injury (REMEDIALIV)

The aim of the REnal Insufficiency Following Contrast MEDIA Administration TriaL IV (REMEDIAL IV) is to test whether the use of the DyeVert system is effective in reducing CI-AKI rate in ACS patients undergoing urgent/immediate (within 2 hours) invasive diagnostic and/or interventional cardiovascular procedures. The DyeVert™ system (Osprey Medical Inc., …

myocardial infarction
medical therapy
acute coronary syndrome
ischemia
angiography
  • 0 views
  • 26 Mar, 2022
  • 1 location
Optical CoherenCe Tomography-gUided Coronary Intervention in Patients With Complex lesIons: a Randomized Controlled Trial (OCCUPI Trial)

There is no definite conclusive work about the benefit of OCT-guided PCI, which should be determined in complex PCI, assuming better stent optimization by OCT. In the study, we will explore the clinical implication of OCT-guided PCI of complex lesions.

chest pain
unstable angina
heart disease
in stent restenosis
stable angina
  • 6 views
  • 13 Feb, 2022
New Technologies for Intensive Prevention Programs - NET-IPP (NET-IPP)

In a randomized trial patients hospitalized for myocardial infarction are prospectively enrolled and assigned to either a web-based intensive prevention program or usual care (1 : 1 randomization). The web-based program includes telemetric transmission of data on cardiocascular risk factors (physical activity, blood pressure, body weight) by patients to the …

myocardial infarction
infarct
  • 0 views
  • 15 Feb, 2022
  • 1 location
Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease

Comparison of Angiography-derived Fractional FLow Reserve And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with CoRonary Artery Disease

stenosis
revascularisation
angiography
intravascular ultrasound
heart disease
  • 0 views
  • 24 Jan, 2021
  • 12 locations