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Found 101 clinical trials
Effect of Surgical Revascularization on Hemorrhagic Moyamoya Disease

Moyamoya Disease(MMD), also known as spontaneous basilar artery occlusion, is characterized by the gradual thickening of arterial intima at the distal carotid artery and the proximal portion of anterior/middle cerebral artery, the gradual stenosis or occlusion of arterial lumen, and the compensatory expansion of basilar cerebral perforating arteries. Cerebral infarction …

cerebral infarction
stenosis
blood type
infarct
basilar artery occlusion
  • 21 views
  • 22 Jan, 2021
  • 1 location
Endovascular Therapy for Low NIHSS Ischemic Strokes

This study will test the hypothesis that patients presenting within 8 hours of onset with cerebral ischemia in the setting of proximal large vessel occlusions (LVO) and low baseline NIHSS scores (0-5) will have better 90-day clinical outcomes (mRS distribution) with immediate mechanical thrombectomy (iMT) compared to initial medical management …

stroke
thrombectomy
magnetic resonance angiography (mra)
plasminogen
ischemia
  • 0 views
  • 15 Feb, 2021
  • 2 locations
Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study

Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance in stroke prevention strategies. Instead of relying on non-specific criteria for stroke risk assessment, the investigators propose to identify individuals with high-risk of embolic …

  • 0 views
  • 16 May, 2021
  • 1 location
Periodontal Treatment and Ischemic Stroke

A bulk of observational evidence suggests an association between periodontitis and recurrent vascular events in ischemic stroke survivors. One plausible biological mechanism relies on the systemic inflammatory response posed by periodontitis together with changes in the normal function of the vascular endothelium which might lead to recurrence in these population. …

root planing
periodontal treatment
severe periodontal disease
  • 0 views
  • 17 Jul, 2021
  • 1 location
Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction

This study will assess the effect of active postoperative temperature management and its effect on the cognitive function in patients following coronary artery bypass graft (CABG) surgery to determine if active postoperative temperature management to maintain normothermia reduces postoperative cognitive dysfunction (POCD) in this population. Additionally, the investigators will explore …

bypass graft
hypothermia
heart surgery
coronary artery bypass graft
cognitive impairment
  • 10 views
  • 03 Apr, 2021
  • 1 location
Post Implantation Syndrome and Administration on NSAIDs in Patients Undergoing EVAR for AAA

INTRODUCTION Post-implantation syndrome is the clinical and biochemical expression of an inflammatory response following endovascular repair of an aortic aneurysm. PIS is mainly a clinical condition associated with the implantation of an endograft and is diagnosed by the presence of fever accompanied by elevated WBC count above normal without any …

aortic aneurysm
interleukin-6
  • 7 views
  • 22 Jan, 2021
  • 1 location
Study of Apixaban in Patients Receiving Hemodiafiltration

Atrial fibrillation (AF) is a prevalent and serious disease in hemodialysis (HD) patients. Untreated AF increases the risk of deaths related to cardiovascular events and multiplies the risk of strokes by 5. Anticoagulation with warfarin significantly reduces the incidence of ischemic strokes in the general population, has a long half-life, …

warfarin
fibrillation
anticoagulation therapy
stroke
rivaroxaban
  • 0 views
  • 19 Jul, 2021
  • 1 location
Efficacy of a Didactic Intervention in Anticoagulated Patients (TAOPE Study)

Background: Oral anticoagulant drugs represent an essential tool in thrombo-embolic events prevention. Most used are vitamin K antagonists (VKA), which plasma level is monitored measuring prothrombin time using the International Normalized Ratio. If it takes values out of recommended range, the patient will have a higher risk of suffering from …

  • 1 views
  • 22 Jan, 2021
  • 2 locations
Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.

The purpose of this study is to determine whether nitric oxide is effective in the treatment of acute kidney injury in cardiac surgical patients with sign and laboratory data suggesting endothelial dysfunction undergoing prolonged cardiopulmonary bypass.

renal injury
replacement therapy
heart surgery
kidney function tests
renal replacement
  • 19 views
  • 07 Mar, 2021
Improved Prediction of Recurrent Stroke and Detection of Small Volume Stroke

patient will however suffer from a more distal occlusion resulting in small volume stroke or a transient ischemic attack (TIA). Small ischemic lesions are hard to detect with current acute stroke

ct scan
stroke
acute stroke
ischemia
transient ischemic attack
  • 1 views
  • 23 Jan, 2021
  • 2 locations