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Found 101 clinical trials
Sleep for Stroke Management and Recovery Trial

The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at …

apnea
ischemic stroke
recurrent strokes
acute stroke
obstructive sleep apnea
  • 1496 views
  • 19 Apr, 2021
  • 138 locations
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

) in reduction of risk of stroke or transient ischemic attack (TIA), brain infarctions and cognitive decline using a 2-MHz diagnostic probe with a maximal diagnostic energy on the reduction of risk of

stroke
carotid artery stenosis
endarterectomy
MRI
stenosis
  • 6 views
  • 26 Jan, 2021
  • 2 locations
The Impact of a Smartphone-based Personalized Intervention on Cognitive and Cerebrovascular Health in CIRCLE-CHINA

This smartphone-based personalized multiple intervention study aims to prevent cognitive impairment and reduce dementia and cerebrovascular events in 45-74 year old persons with high risk of stroke in China. The investigators plan to monitor and manage participants' behavioral and health (vascular risk factors control, sleep quality, mental health and cognitive …

heart disease
atrial fibrillation
cognitive training
nervous system disorder
cognitive decline
  • 0 views
  • 31 Jul, 2021
  • 1 location
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

atrial fibrillation
clopidogrel
fibrillation
anticoagulation therapy
ticagrelor
  • 112 views
  • 23 Sep, 2021
  • 80 locations
Secondary Prevention By Structured Semi-Interactive Stroke Prevention Package in INDIA (SPRINT INDIA) Study

Recurrent stroke, cardiovascular morbidity and mortality are important causes of poor outcome in patients with index stroke. According to the INTERSTROKE study, 80% of stroke are preventable due to the presence of modifiable risk factors. However, the lack of knowledge that stroke and cardiovascular diseases are preventable is a major …

intracerebral hemorrhage
ischemic stroke
infarct
MRI
recurrent strokes
  • 0 views
  • 05 Aug, 2021
  • 1 location
Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease

Background: In patients with chronic obstructive pulmonary disease (COPD) and concomitant cardiovascular conditions cardio-selective beta-blockers reduce mortality and can be used without significant negative effects on lung function or respiratory symptoms. Observational studies indicate that beta-blocker therapy in COPD even without overt cardiovascular disease, is associated with reduced risk for …

asthma
pulmonary function test
bronchodilator
copd exacerbation
spirometry
  • 21 views
  • 26 Jan, 2021
  • 3 locations
GLP-1 and Hyperoxia for Organ Protection in Heart Surgery

Patients undergoing open heart surgery are at risk of suffering damage to the heart, brain and kidneys. This study is designed as a 2-by-2 randomized clinical trial with the purpose of investigating the organ protective effects of the glucagon-like-peptide-1 (GLP-1) agonist Exenatide versus placebo and restrictive versus liberal oxygenation during …

heart disease
glp-1
glucagon
ischemic heart disease
arterial disease
  • 36 views
  • 25 Apr, 2021
  • 1 location
Smoking Cessation Intervention After Stroke or Transient Ischaemic Attack.

advise on smoking cessation during hospitalisation for stroke or transient ischemic attack. The aim of the study was to assess if an intensive smoking cessation program made more

stroke
transient ischemic attack
acute stroke
  • 12 views
  • 07 Nov, 2020
  • 1 location
AcoArt VI / Vertebral Artery Ostium Stenosis in China

The purpose of this study is to determine whether DEB is not inferior to common bare metal stent using under in long-term vessel patency and inhibiting restenosis in Vertebral Artery Ostium Stenosis

stenosis
angiography
  • 0 views
  • 26 Jan, 2021
  • 1 location
A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device

The purpose of this research is to determine if two non-invasive brain stimulation techniques, muscle stimulation of the arm and neuro-stimulation through the tongue, can increase the extent of stroke recovery.

stroke rehabilitation
electrical stimulation
MRI
  • 25 views
  • 17 Aug, 2021
  • 1 location