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Found 1250 clinical trials
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Sternal Cerclage (sternal bone closure after open heart surgery)

The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).

coronary revascularization
revascularisation
acute coronary syndrome
  • 1160 views
  • 05 Feb, 2021
  • 1 location
featured
A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease

A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease

  • 64 views
  • 25 Mar, 2021
  • 1 location
featured
TIGRIS

TIGRIS

  • 120 views
  • 25 Mar, 2021
  • 1 location
Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)

Extracorporeal membrane oxygenation (ECMO) is of great value in supporting patients with cardiac shock. More than 80% ECMO patients will develop renal catastrophe that continuous renal replacement therapy (CRRT) is required. The evidence is conflict as to whether early CRRT improves outcomes. Early CRRT before a definite indication developed may …

  • 0 views
  • 23 Jan, 2021
  • 1 location
REMOTE Ischemic Perconditioning Among Acute Ischemic Stroke Patients ( REMOTE-CAT)

, consisting on brief episodes of transient limb ischemia, represents a new paradigm in neuroprotection. It can be categorized in pre-, per- or postconditioning, depending on the moment of application

infarct
alteplase
ischemia
stroke
plasminogen
  • 1 views
  • 23 Jan, 2021
  • 2 locations
Outcome in Patients Treated With Intraarterial Thrombectomy - optiMAL Blood Pressure Control (OPTIMAL-BP)

guideline is adopted even though the possibility of intracerebral hemorrhage or reperfusion injury by high blood pressure. On the other hand, too low blood pressure can worsen cerebral ischemia.

thrombectomy
ischemia
stroke
intracerebral hemorrhage
arterial occlusion
  • 0 views
  • 23 Jun, 2021
  • 1 location
Optimal antiPlatelet Therapy for High Bleeding and Ischemic RISK Patients Trial

Current guidelines recommend that patients with ACS undergoing stent implantation might be offered extended DAPT treatment for up to 30 months if necessary. Therefore, we designed a prospective, multicenter, randomized, placebo-controlled trial among ACS patients with high-risk on ischemic and bleeding who received a new generation of DES and received …

  • 8 views
  • 26 Jan, 2021
  • 1 location
Robotic Versus Conventional or Endoscopic Nipple Sparing Mastectomy for Breast Cancer

This study will retrospectively collect and evaluate the surgical outcomes of robotic nipple sparing mastectomy (R-NSM) compared with endoscopic assisted NSM (E-NSM) or conventional NSM (C-NSM) in the management of breast cancer. Multi-centers pooled data analysis would be performed for comparisons of R-NSM compared with C-NSM or E-NSM.

breast cancer
carcinoma in situ
mastectomy
breast cancer staging
cancer
  • 0 views
  • 25 Jan, 2021
  • 11 locations
Delirium Reduction by Volatile Anesthesia in Cardiac Surgery

Parallel group, prospective, randomized, controlled, single-blinded trial. The aim of our study is to test the hypothesis that volatile anesthesia would reduce the incidence of early postoperative delirium in patients undergoing cardiac surgery with CPB as compared to TIVA.

propofol
anesthesia
heart surgery
postoperative delirium
  • 18 views
  • 23 Jan, 2021
  • 3 locations
Integrated Platform for Multimodal Patient Monitoring and Therapy Support in ICU Patients

In neurocritical care, besides the standard intensive care monitoring, even more data are obtained from the very complex pathophysiological changes in brain disease. Medical staff for decision-making cannot integrate the huge amount of clinical data generated every second and visualized on different monitors, anymore. Lack of data integration and usability …

  • 0 views
  • 09 Apr, 2021
  • 1 location