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Found 247 clinical trials
Perioperative Management in Gynaecological Carcinoma Surgery

This study is to determine the effect of perioperative treatment with intravenous iron and tranexamic acid on the reduction of intraoperative and postoperative RBC transfusions in gynaecological

  • 0 views
  • 11 Mar, 2022
  • 1 location
Clinical Curative Effect Evaluation Study of Treatment of Oral Deferiprone Tablets in Aceruloplasminaemia Patients

Aceruloplasminemia is an autosomal recessive disorder characterized by iron deposition in the brain and visceral organs. Deferiprone was used to treat aceruloplasminemia in previous study. In

  • 0 views
  • 20 Feb, 2022
  • 1 location
Pomalidomide for the Treatment of Bleeding in HHT (PATH-HHT)

require parenteral iron infusions or blood transfusions. A total of 159 patients will be randomized 2:1 to treatment with oral pomalidomide or matching placebo for 24 weeks. Mean change from baseline to

parenteral infusion
platelet count
blood transfusion
epistaxis
iron
  • 11 views
  • 21 Jul, 2022
  • 10 locations
Bevacizumab In Hereditary Hemorrhagic Telangiectasia

This research study is studying to see whether bevacizumab may treat chronic bleeding and iron deficiency anemia in Hereditary Hemorrhagic Telangiectasia (HHT). Hereditary Hemorrhagic

  • 0 views
  • 10 Jul, 2021
  • 1 location
Impact of Transferrin Saturation Guided Maintenance Treatment on Quality of Life in HFE Haemochromatosis

proton pump inhibitors are widely used as chronic medication, and because they can significantly modify iron absorption, patients will be stratified according to the use of proton pump inhibitors and

  • 11 views
  • 26 Jul, 2021
  • 11 locations
Coronary Artery Disease in Patients With Friedreich's Ataxia

Friedreich's ataxia is a debilitating, inherited disease cause by mutations in a protein called frataxin (FXN). FXN is one of several proteins that controls the production of iron-sulfur

cardiomyopathy
deficiency
iron
  • 1 views
  • 23 Mar, 2022
  • 1 location
Endoscopically-delivered Purastat to Treat Bleeding Caused by Radiation Proctopathy

) requiring either tablet or intravenous (IV) iron replacement, or blood transfusion. There are very few safe, effective, evidence-based treatments available for RP. Purastat is a new haemostatic

  • 4 views
  • 29 Sep, 2021
  • 1 location
Efficacy and Safety oF FErric CarboxymalTose in Patients With Advanced Gastric Cancer(EFFECT-AGC)

The main objective of this study is to evaluate the efficacy and safety of IV FCM(ferric carboxymaltose) in patients with AGC receiving palliative chemotherapy. This study will also evaluate the effect of IV FCM on the treatment outcomes of palliative chemotherapy in patients with gastric cancer receiving fluoropyrimidine and platinum-based …

  • 0 views
  • 23 May, 2022
  • 1 location
Micronutrient Bioavailability From Wheat

The purpose of this study is to determine if physical disruption of wheat aleurone cell walls (micro-milling) increases micronutrient availability.

Accepts healthy volunteers
  • 0 views
  • 20 Sep, 2022
  • 1 location
Role of Blood Management in Perioperative Outcomes

There is currently limited information regarding the role of blood management in the benign gynecologic population and specifically, in patients who are scheduled to undergo surgery for fibroids and/or abnormal uterine bleeding. A thorough search through PubMed and clinicaltrials.gov did not reveal any studies on this issue. In 2019 at …

  • 0 views
  • 28 Jul, 2022
  • 1 location