Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 246 clinical trials
Liver Toxicity in Lung Cancer Patients Treated With Immune-checkpoint Inhibitors.

Immune-checkpoint inhibitors have recently become available as a new therapy for a variety of cancers. This drugs function by boosting the anti-cancer immune response, but unfortunately, may cause off-target, non-specific immune activation, resulting in liver and gut toxicity. In order to understand the development of liver immune-related adverse events we …

lung carcinoma
advanced lung cancer
cancer
cancer chemotherapy
  • 0 views
  • 22 Mar, 2022
  • 3 locations
Early Detection of Long-term Diabetic Complications in Children and Adolescents With Type 1 Diabetes

Aims: To investigate early markers of arterial stiffness and nerve dysfunction and the association to an extended glucose metabolic profile comprising glucose control (current and past), glucose variability and insulin sensitivity in children and adolescents with type 1 diabetes (T1D). Background: Most Danish children and adolescents with T1D do not …

diabetic complications
nephropathy
insulin
diabetes
  • 0 views
  • 26 May, 2022
  • 1 location
Is Levothyroxine Alone Adequate Thyroid Hormone Replacement?

Patients taking thyroid hormone replacement after thyroid removal surgery often report feeling differently than they did prior to taking thyroid hormone. The symptoms can include fatigue, worsening mood or subjective "brain fog" where the patient feels like their thinking is just not as sharp as it was previously. Multiple studies …

thyroxine
thyroidectomy
thyroid hormones
levothyroxine therapy
replacement therapy
  • 200 views
  • 24 Feb, 2022
  • 1 location
Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly (SmartAge)

Cognitive disorders increase with age and in the presence of metabolic diseases such as Type 2 Diabetes Mellitus (T2DM). In addition, digestive disorders, changes in dietary pattern and decreased activity negatively influence the microbiome. The hypothesis is that pharmacological intervention with metformin will modify the composition of the gut microbiota …

type 2 diabetes mellitus
metformin
continuous glucose monitoring
  • 0 views
  • 04 Oct, 2022
  • 1 location
Unravelling the Alteration of Brain Structure and Function in Parkinson´s Disease With Ultra-high Field MRI (7TPD)

Parkinson's Disease (PD) is a neurodegenerative disease characterized by a range of disabling motor- and non-motor symptoms caused by a loss of neurons in neuromodulatory brainstem nuclei. Typical motor symptoms include bradykinesia, rigidity and tremor. Non-motor symptoms are diverse and include REM sleep behaviour disorder, hyposmia, autonomic dysfunction, depression, apathy …

apathy
bradykinesia
dopamine
cognitive impairment
motor symptoms
  • 41 views
  • 30 May, 2022
  • 2 locations
bAriatric sUrgery Registration in wOmen of Reproductive Age

The use of bariatric surgery has risen subsequently over the last decade, especially in women of reproductive age. (Unplanned) pregnancies in this subgroup are not rare because of e.g. an increased fertility (because of the weight loss) and a possible ineffectiveness of contraceptives (because of a malabsorption in the intestine). …

high risk pregnancy
  • 6 views
  • 15 May, 2021
  • 1 location