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Found 52 clinical trials
Iron Infusion Into a Vein Compared to Iron Tablet Taken by Mouth for Treating Iron Deficiency Anemia in Pregnancy (IVON) (IVON)

deficiency anaemia (IDA). The earliest of these, iron dextran is not commonly used because of its potential to cause anaphylactic reactions. Newer preparations have been found to be safer and their use for

Accepts healthy volunteers
  • 10 Jul, 2022
  • 10 locations
Multi-center Trial of Ferric Derisomaltose in Children 0 to <18 Years of Age With Iron Deficiency Anemia

Several clinical trials have been reported for ferric derisomaltose where it has been shown to be well tolerated and to improve markers of IDA. All clinical trials with ferric derisomaltose have been performed in adults, however, IDA is not specific to the adult population. In fact, children are likely to …

  • 08 Apr, 2023
Treatment of Non-Anemic Iron Deficiency in Pregnancy: a Double-Blind Randomized Control Trial

The objective is to investigate the treatment of non-anemic iron deficiency (NAID) and the impact on development of anemia later in pregnancy. Anemia in the third trimester has been identified

Accepts healthy volunteers
  • 29 Oct, 2022
Phase IIb Pre-pivotal Study to Assess the Safety and Efficacy of the IUB SEAD™ Device in Women Suffering From Heavy Menstrual Bleeding (HMB) (HMB)

One of the AUB symptoms, heavy menstrual bleeding (HMB), can lead to iron deficiency and iron deficiency anemia and in acute and severe cases, can necessitate emergency medical care. This

follicle stimulating hormone
endometrial ablation
  • 21 Oct, 2022
  • 1 location
Bevacizumab In Hereditary Hemorrhagic Telangiectasia

This research study is studying to see whether bevacizumab may treat chronic bleeding and iron deficiency anemia in Hereditary Hemorrhagic Telangiectasia (HHT). Hereditary Hemorrhagic

  • 10 Jul, 2021
  • 1 location
Postoperative Replacement of Intraoperative Iron Losses (POREIIL)

By performing a randomized, blinded placebo controlled exploratory trial we speculate that replacement of perioperative, bleeding-induced iron losses with ferric carboxymaltose immediately after the surgical procedure can replenish iron with increased hemoglobin levels and reduce the amount of pRBCs transfused in the postoperative period (30 days post surgery).

  • 19 Apr, 2022
  • 1 location
Perioperative Iron for Colorectal Cancer (PICoC Study) (PICoC)

The PICoC study aims to investigate whether oral ferric maltol given postoperatively offers an improvement in patient and clinician reported outcomes compared to standard care.

  • 11 Jul, 2022
  • 1 location
Efficacy and Safety oF FErric CarboxymalTose in Patients With Advanced Gastric Cancer(EFFECT-AGC)

The main objective of this study is to evaluate the efficacy and safety of IV FCM(ferric carboxymaltose) in patients with AGC receiving palliative chemotherapy. This study will also evaluate the effect of IV FCM on the treatment outcomes of palliative chemotherapy in patients with gastric cancer receiving fluoropyrimidine and platinum-based …

  • 23 May, 2022
  • 1 location
Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality (FAIR-HF2)

The purpose of this study is to determine whether intravenous iron supplementation using ferric carboxymaltosis (FCM) reduces hospitalisation and mortality in patients with iron deficiency and

chronic heart failure
systolic heart failure
  • 24 Feb, 2022
  • 32 locations
Reducing Anemia in Pregnancy in India: the RAPIDIRON Trial (RAPIDIRON)

women with iron deficiency anemia (IDA). Reducing Anemia in Pregnancy in India: the RAPIDIRON Trial is a 3-arm, randomized-controlled trial designed to assess if a single dose of an intravenous (IV

  • 11 May, 2022
  • 4 locations