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Found 5 clinical trials
A Trial of Ipatasertib in Combination With Atezolizumab

This is a single centre, proof-of-concept phase I trial of atezolizumab in combination with ipatasertib. There are two parts to this study, the dose escalation phase (Part A) and the dose

serum bilirubin
cancer
measurable disease
platelet count
aptt
  • 15 views
  • 25 Jan, 2021
  • 1 location
Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients

This is an open label, single arm, multicenter, phase Ib study to evaluate the safety and clinical activity of the combination of ipatasertib, trastuzumab and pertuzumab in patients with

PIK3CA
pertuzumab
trastuzumab
breast adenocarcinoma
metastasis
  • 0 views
  • 25 Jan, 2021
  • 6 locations
Ipatasertib Plus Non-Taxane Chemotherapy for Advanced or Metastatic Triple-Negative Breast Cancer

This is a multicenter, open-label, non-comparative, three-arm, phase IIa trial of Ipatasertib (GDC-0068) in combination with non-taxane chemotherapy agents for taxane-pretreated unresectable

  • 0 views
  • 05 Dec, 2020
  • 17 locations
Ipatasertib in Combination With Carboplatin Carboplatin/Paclitaxel or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer

This phase I trial studies best dose of ipatasertib and how well it works with carboplatin with or without paclitaxel in treating patients with triple negative breast cancer that has spread to

  • 4 views
  • 25 Jan, 2021
  • 1 location
AKT Inhibitor Ipatasertib With Endocrine and CDK 4/6 Inhibitor for Patients With Metastatic Breast Cancer (TAKTIC)

This research is looking to find out if the combination of Ipatasertib with Aromatase inhibitor or Fulvestrant can be an effective treatment for breast cancer.

fulvestrant
estrogen
tamoxifen
metastasis
endocrine therapy
  • 6 views
  • 25 Jan, 2021