Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 242 clinical trials
A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia

This is a Phase 2b study investigating the efficacy and safety of mesdopetam as adjunct therapy on daily ON-time without troublesome dyskinesia in patients with Parkinson disease. Mesdopetam is

apomorphine
levodopa
dyskinesia
  • 0 views
  • 24 Mar, 2022
  • 28 locations
Mulligan's Mobilization and Proprioceptive Neuromuscular Facilitation Technique in Sacroiliac Joint Dysfunction

This study will aim to compare the effects of mulligan mobilization and PNF on pain and disability with patients of SIJ dysfunction and will be helpful for clinical physiotherapist to choose more effective treatment protocol for patients as there are fewer researches on comparison of these techniques.

Accepts healthy volunteers
  • 0 views
  • 09 May, 2022
Efficacy of an Early Phase Single Bolus r-SAK for Acute Myocardial Infarction: a Multi-center Randomized Clinical Trial

This study was a prospective, multicenter, randomized, controlled, excellence clinical trial. Subjects meeting the inclusion/exclusion criteria were randomly assigned 1:1 to r-SAK group or the control group (normal saline). Emergency coronary angiography was performed and cardiac magnetic resonance imaging was performed 5 days after surgery, followed up to 30 days. …

  • 0 views
  • 28 Apr, 2022
  • 3 locations
Transcranial Ultrasound Therapy of Essential Tremor

Context. Essential tremor (ET) is a common disease, disabling in severe forms and resistant to drug treatment. In patients with severe ET, invasive neurosurgical technique such as deep brain stimulation of the Ventral Intermediate (VIM) nucleus of the thalamus is used. Focused ultrasound therapy, creating a small lesion of VIM …

brain stimulation
MRI
movement disorder
depression
  • 345 views
  • 24 Jan, 2021
  • 1 location
Variability of the Unique Fiber Potentials of a Spastic Muscle Treated With Botulinum Toxin (JITTOX)

The main objective is to study the variability and evolution of single-fiber jitter and fiber density (FD) electrophysiological parameters in a spastic muscle during botulinum toxin type A (BTA) treatment in hemiplegic patients after stroke, according to primary or multi-injected status. The secondary objectives of this study are: To establish …

Accepts healthy volunteers
  • 15 views
  • 26 Mar, 2022
  • 1 location
A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Dyskinesia in Cerebral Palsy in Children and Adolescents (RECLAIM-DCP)

hyperkinetic movement disorders, namely chorea in Huntington's disease (HD) and tardive dyskinesia (TD). Currently, there is no approved treatment available for Dyskinesia in cerebral palsy (DCP). The

  • 319 views
  • 16 May, 2022
  • 51 locations
A Study to Test if TEV-50717 is Safe and Effective in Relieving Abnormal Involuntary Movements in Cerebral Palsy

Study TV50717-CNS-30081 is a 55-week study in which patients who have successfully completed the parent study (Study TV50717-CNS-30080) may be eligible to enroll in this study. The primary objective of this study is to evaluate the safety and tolerability of long-term therapy with TEV-50717 in children and adolescents with DCP. …

  • 1 views
  • 24 May, 2022
  • 29 locations
Randomized Controlled Trial of Pyridoxine for Tardive Dyskinesia

Purpose: Tardive dyskinesia (TD) is a involuntary movement disorder that can occur following long term treatment with antipsychotic medications and for which few treatment options exist. This

antipsychotics
dopamine
movement disorder
human chorionic gonadotropin
dopamine antagonist
  • 320 views
  • 01 May, 2022
  • 1 location
Risperidone for the Treatment of Huntington's Disease Involuntary Movements

The purpose of this study is to assess the safety and benefit of risperidone for the treatment of chorea (involuntary movements) in Huntington's disease. Risperidone is commonly used in clinical

chorea
risperidone
involuntary movements
  • 105 views
  • 24 Jan, 2022
  • 1 location
Study in Parkinson's Disease Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components (SHINE)

This is a two-part, double-blind, placebo-controlled, randomized, multicenter Phase 2 clinical trial of JM-010 in patients with Parkinson's Disease.

levodopa
dyskinesia
parkinson's disease
  • 9 views
  • 25 Apr, 2022
  • 3 locations