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Found 21 clinical trials
PRE-VENT Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer

This is a Phase 3 randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of pacritinib in hospitalized patients with severe COVID-19 with or without cancer.

PCR test
covid-19
FIO2
SARS
pao2
  • 117 views
  • 28 Jan, 2021
  • 26 locations
Cannabidiol Treatment for Severe and Critical Coronavirus (COVID-19) Pulmonary Infection

Current management of COVID-19 (coronavirus) is mainly supportive, and respiratory failure from acute respiratory distress syndrome (ARDS) is the leading cause of mortality. Cytokines and chemokines are thought to play an important role in immunity and immunopathology during virus infections. Patients with severe COVID-19 have higher serum levels of pro-inflammatory …

  • 0 views
  • 02 Feb, 2021
  • 1 location
A Study of Melphalan BCNU Vitamin B12b Vitamin C and Stem Cell Infusion in People With Advanced Pancreatic Cancer and BRCA Mutations

The clinical trial is a phase 1, single-arm trial that will evaluate the safety of the investigational treatment on pancreatic cancer in patients who have an inherited, deleterious BRCA1 or BRCA2 genetic alteration. The investigational treatment will involve 2 cycles of a combination of intravenous melphalan, BCNU, low-dose I.V. ethanol, …

  • 0 views
  • 24 Feb, 2021
  • 1 location
Acalabrutinib Venetoclax and Obinutuzumab for Initial Therapy of CLL

This research study is evaluating the combination of three drugs - acalabrutinib, venetoclax, and obinutuzumab -- as a possible treatment for chronic lymphocytic leukemia (CLL). The drugs involved in this study are: Acalabrutinib Venetoclax Obinutuzmab

acalabrutinib
thrombocytopenia
direct bilirubin
anemia
fever
  • 156 views
  • 25 Jan, 2021
  • 3 locations
Pirfenidone Compared to Placebo in Post-COVID19 Pulmonary Fibrosis COVID-19

Study population: Patients with fibrotic lung sequelae after recovery from acute phase of severe COVID19 pneumonia Objectives: To evaluate the effect of pirfenidone administered for 24 weeks in patients who have pulmonary fibrotic changes after suffering severe COVID19 pneumonia, analysed by % change in forced vital capacity (FVC) % fibrosis …

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Ventricular Tachycardia Ablation and Myocardial Scar Characterization With Magnetic Resonance

Previous monocentric experiences have already highlighted the role of preoperative cardiac imaging, in particular of cardiac magnetic resonance (CMR) and tomography (CT), in improving the ablation results of scar-related ventricular tachycardia (VT). A better characterization of scar obtained with high quality CMR images and post processing data with creation of …

  • 0 views
  • 27 Jan, 2021
  • 7 locations
Russian Prospective Multicenter Registry Study of Intravenous Thrombolytic Therapy for Acute Ischemic Stroke

Russian prospective multicenter registry study of intravenous thrombolytic therapy for acute ischemic stroke.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung Esophagus and Lung Lining

Background Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and protein. Cancers of the lung, pleura (lung lining) and esophagus show profound changes in chromatin structure that may affect the course of …

metastasis
withdrawn
esophagus cancer
bronchoscopy
cancer
  • 139 views
  • 27 Jan, 2021
  • 1 location
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

Background Recent advances in cancer research have led to new therapies to treat the disease. It is important to continue these advances and discover new ones. To do that, researchers need tissue samples from solid tumors. This study will collect such samples from people already scheduled to have a procedure …

white blood cell count
solid tumor
solid tumour
cancer
  • 18 views
  • 16 Feb, 2021
  • 1 location
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

Background Endocrine neoplasms (tumors) are among the fastest growing tumors in incidence in the United States. Furthermore, it is often difficult to distinguish between benign or malignant tumors in cancers of the thyroid, parathyroid, adrenal gland, and pancreas. More research is needed to improve detection and treatment options for patients …

parathyroid
cancer
endocrine cancer
biochemical testing
paraganglioma
  • 170 views
  • 19 Feb, 2021
  • 1 location