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Found 388 clinical trials
Effect of Melatonin on Cardiometabolic Risk- FULL

In a 12 week double-blind, placebo-controlled randomized trial, 120 subjects with obesity (BMI30 kg/m2) and pre-diabetes (HbA1c, 5.7-6.4%) will be randomly assigned 1:1 to receive either placebo or 2 mg of controlled-release melatonin, taken orally every evening 1 hour before bed. The investigators will assess melatonin's effect on insulin sensitivity …

body mass index
insulin
hemoglobin a1c
insulin sensitivity
cytokines
  • 6 views
  • 23 Jan, 2021
7-valent Pneumococcal Conjugated Vaccination

Hypothesis: the efficacy of 2 doses 7-valent PCV is equivalent to 1 dose 7-valent PCV.

  • 0 views
  • 07 Nov, 2020
Phase Study of Tyroserleutide for Injection in Hepatocellular Carcinoma(HCC) Patients

group. Each group includes 25 subjects, who have hepatic-cellular carcinoma accompanied with branch vein thrombosis. They receive investigational drug 40 days after resection surgery. Each

fluorouracil
thrombosis
  • 1 views
  • 07 Nov, 2020
  • 1 location
Russian Prospective Multicenter Registry Study of Intravenous Thrombolytic Therapy for Acute Ischemic Stroke

Russian prospective multicenter registry study of intravenous thrombolytic therapy for acute ischemic stroke.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Prospective Evaluation of Infants With Spinal Muscular Atrophy:

children with type 1, 2 or 3 and age appropriate controls. There is no investigational drug and no specific intervention in this study. Rather, the investigators will document outcomes related to current

muscle atrophy
  • 28 views
  • 25 Jan, 2021
Alzheimer's Prevention Registry: A Program to Accelerate Enrollment Into Studies

in a research study. Study opportunities may include surveys, healthy lifestyle interventions (e.g., diet, exercise), memory & thinking tests, brain scans, and investigational drug trials. To

alzheimer's disease
  • 29 views
  • 02 Feb, 2021
  • 1 location
Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease Type C

This study will evaluate clinical and laboratory tests that might be useful in determining if an investigational drug can slow the progression of Niemann-Pick Disease, Type C (NPC), a genetic

  • 1 views
  • 15 Sep, 2021
  • 3 locations
Initial and Chronic Methicillin Resistant Staphylococcus Aureus (MRSA) Infection in Cystic Fibrosis (CF)

This study aims to examine features of MRSA that are associated with chronic MRSA infection and bacterial persistence despite IV antibiotic therapy. Subjects are asked to expectorate sputum and complete CF symptom diaries both at beginning and end of IV therapy.

respiratory symptom
respiratory symptoms
doxycycline
linezolid
methicillin
  • 33 views
  • 25 Feb, 2021
  • 3 locations