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Found 132 clinical trials
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery

This randomized phase III trial studies standard or comprehensive radiation therapy in treating patients with early-stage breast cancer who have undergone surgery. Radiation therapy uses high-energy x rays to kill tumor cells. It is not yet known whether comprehensive radiation therapy is more effective than standard radiation therapy in treating …

estrogen
ductal carcinoma in situ
sentinel lymph node biopsy
mastectomy
sentinel node
  • 784 views
  • 24 Jan, 2021
  • 127 locations
Prospective Trial of Digital Breast Tomosynthesis (DBT) in Breast Cancer Screening.

The accuracy of standard two dimension digital mammography (2DDM) in breast cancer screening is limited because of superimposition of normal breast structures onto a two dimensional image. Mammography signs of breast cancer may be obscured, resulting in delay in the diagnosis of breast cancer. Conversely, superimposition of normal tissues may …

mammogram
  • 1 views
  • 23 Jan, 2021
Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

Although the results obtained from ECOG E5194 cohort 1 (criteria: mammographically detected low- or intermediate-grade DCIS, measuring less than 2.5 cm with margins 3 mm) and RTOG 9804 trial (the same enrolled clinicopathological features to cohort 1 of ECOG E5194 trial) demonstrated that the 7-year ipsilateral breast tumor recurrence (IBTR) …

estrogen
tamoxifen
mammogram
estrogen receptor
radiotherapy to breast
  • 9 views
  • 23 Jan, 2021
  • 1 location
Sentinel Lymph Node Procedure in Ipsilateral Invasive Breast Cancer Relapse

Sentinel lymph node biopsy (SLNB) has become the standard procedure for staging of patients with clinically node-negative breast cancer. Breast-conserving surgery (BCS) has also been a standard treatment for patients with early breast cancer. However, approximately 10% of patients with BCS develop ipsilateral breast tumor recurrence (IBTR), and mastectomy or …

sentinel lymph node biopsy
mastectomy
sentinel node
metastasis
breast tumor
  • 3 views
  • 22 Jan, 2021
  • 4 locations
Examining Bioactivity of PVSRIPO in Invasive Breast Cancer

This is a pilot study to examine PVSRIPO bioactivity in tumor tissue after intratumoral administration of PVSRIPO in women with invasive breast cancer.

estrogen
residual tumor
triple-negative breast cancer
mammogram
progesterone
  • 1 views
  • 25 Jan, 2021
  • 1 location
Density Lowering Effect of "OFS Add on to TMX"(DELFINO Trial)

DELFINO tial is designed to investigate the role of "OFS add on to TMX ", based on MMG density as a surrogate marker in premenopausal women Premise - MMG density as a surrogate marker of hormone therapy Assumption - "Add on OFS to TMX" would have further decrease of density …

endocrine therapy
hormone therapy
  • 1 views
  • 22 Jan, 2021
Prospective Multicentric Study Evaluating the Surgical Treatment by Mastectomy With Immediate Prosthetic Breast Reconstruction in Patients With Breast Cancer and Receiving Adjuvant Therapy by TomoTherapy +/-Chemotherapy.

receiving adjuvant therapy by TomoTherapy +/-Chemotherapy. Patients with non-inflammatory and non-metastatic invasive mammary carcinoma will be included in this study. The study procedure

carcinoma
mastectomy
  • 0 views
  • 28 Jan, 2021
  • 2 locations
Pyrotinib Trastuzumab Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer

This study aims to evaluate the efficacy and safety of pyrotinib in combination with trastuzumab, pertuzumab and nab-paclitaxel as neoadjuvant therapy in early stage or locally advanced HER2-positive breast cancer.

estrogen
estrogen receptor
progesterone
progesterone receptor
pertuzumab
  • 0 views
  • 24 Jan, 2021
  • 1 location
Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma

This study is a randomized trial of hypofractionation (short-course) radiation therapy versus conventional radiation therapy in women who have undergone mastectomy and immediate breast reconstruction. The investigators will assess cosmetic and reconstruction outcomes, lymphedema, cancer status, side effects, and oncologic outcomes.

breast carcinoma
mastectomy
invasive breast cancer
breast reconstruction
carcinoma
  • 35 views
  • 27 Jan, 2021
  • 13 locations
A "Window Trial" on Curcumin for Invasive Breast Cancer Primary Tumors

The purpose of this study is to determine whether oral administration of curcumin causes biological changes in primary tumors of breast cancer patients.

estrogen
mammogram
invasive breast cancer
primary tumor
  • 0 views
  • 05 Mar, 2021
  • 1 location