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Found 132 clinical trials
MRI Characterization of Mammographically Detected DCIS

This is a single institution, prospective observational clinical trial for women with mammographically identified calcifications that may represent ductal carcinoma in situ (DCIS). The purpose of this study is to determine whether quantitative, multiparametric breast MRI performed prior to surgical resection can biologically characterize this common pre-invasive malignancy, ductal carcinoma …

  • 6 views
  • 27 Jan, 2021
  • 2 locations
Clinical Information and Biospecimen Collection From Patients With Recurrent or Stage IV Breast Cancer

This trial collects clinical information and tissue and blood samples from patients with breast cancer that has come back or is stage IV. Collecting clinical information and biospecimen samples to create a registry may help doctors better understand the mechanism of tumor spread and determine why people respond differently to …

breast cancer
invasive breast cancer
cancer
local anesthetic
pleural fluid analysis
  • 1 views
  • 26 Jan, 2021
  • 6 locations
Adherence of Hispanic / Latina Breast Cancer - Patients to Adjuvant Aromatase Inhibitors

This is an observational trial designed to assess prospectively the adherence rate to AIs among women with invasive breast cancer (stages I-III) currently receiving AI adjuvant therapy after

aromatase inhibitor
metastasis
adjuvant therapy
invasive breast cancer
immunostimulant
  • 22 views
  • 23 Jan, 2021
  • 1 location
Assessment of Complete Pathologic Response After Neoadjuvant Chemotherapy for Breast Cancer

accurately predict complete pathologic response (pCR) in women with triple negative or HER2- positive breast cancer. pCR is defined as having no residual invasive breast cancer or ductal carcinoma in situ

breast cancer
carcinoma
erbb2
invasive breast cancer
core needle biopsy
  • 0 views
  • 25 Jan, 2021
  • 1 location
IORT-Breast at MCNH

age and older who have early stage, low risk Invasive Breast Cancer (IBC). Clinical trials have shown IORT to be non-inferior to whole breast radiation, however some concern continues with rates of

  • 0 views
  • 26 Jan, 2021
  • 1 location
Factors Affecting Functionality in Breast Cancer Survivors

Breast cancer is the most frequent cancer type in women globally. In conjunction with the new developments, breast cancer survival has increased therefore the management of long-term complications has gained importance. Breast cancer survivors can face the loss of muscle strength, increased fatigue and diminished physical function associated with treatment-related …

body mass index
breast cancer
cancer surgery
cancer
immunostimulant
  • 0 views
  • 27 Jan, 2021
  • 2 locations
Predictors of Response to Neoadjuvant Docetaxel-Carboplatin Chemotherapy for Patients With Stage II and III Triple Negative Breast Cancer

breast carcinoma into five subtypes: luminal A and B, normal breast-like, HER2/neu overexpressing and basal-like subtypes, with clinical implications. Later on, a new subtype, the claudin-low, has been

BRCA1
carcinoma
advanced breast cancer
docetaxel
erbb2
  • 0 views
  • 25 Jan, 2021
  • 1 location
Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

The goals of this prospective, observational cohort study are to determine the feasibility of implementing paclitaxel therapeutic drug monitoring for cancer patients and explore the relationship between paclitaxel drug exposure and the development of neuropathic symptoms. This trial studies if paclitaxel can be consistently measured in the blood of patients …

metastasis
bevacizumab
atezolizumab
solid tumour
squamous cell carcinoma
  • 0 views
  • 28 Jan, 2021
  • 1 location
Molecular Profiling After Neoadjuvant Chemotherapy for Triple-negative Breast Cancer

Neoadjuvant chemotherapy (NACT) can induce complete pathologic response (pCR) in approximately 35-55% of patient with triple-negative breast cancer (TNBC). These patients have excellent long term survivals. On the other hand patients with residual disease exhibit a high rate of local or metastatic. Although it has been successful in some regards, …

breast cancer
HER2
erbb2
invasive breast cancer
mastectomy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Prospective Feasibility Study Applying the ACOSOG Z0011 Criteria to Chinese Patients

In patients undergoing breast-conserving surgery and having positive sentinel lymph nodes (SLNs), the ACOSOG Z0011 trial showed equivalent overall survival(OS) and disease-free survival(DFS) outcomes for patients receiving SLN dissection (SLND) alone and those receiving axillary lymph node dissection (ALND). We conducted a prospective single-arm study to confirm the applicability of …

axillary lymph node dissection
breast-conserving surgery
invasive breast cancer
  • 0 views
  • 23 Jan, 2021
  • 1 location