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Found 116 clinical trials
QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

This is a Phase II/III, open-label, single-arm, multicenter study of intravesical BCG plus N-803 in patients with BCG unresponsive high grade non-muscle invasive bladder cancer (NMIBC). All

invasive bladder cancer
bcg vaccine
transitional cell carcinoma
carcinoma
cancer
  • 290 views
  • 19 Mar, 2021
  • 36 locations
Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer

This is a randomized, open-label, window of opportunity platform study in patients with muscle-invasive bladder cancer (MIBC) deemed ineligible to receive cisplatin-based neoadjuvant

bladder carcinoma
invasive bladder cancer
radical cystectomy
transitional cell carcinoma
carcinoma
  • 10 views
  • 01 Mar, 2021
  • 1 location
Neoadjuvant Atezolizumab in Localized Bladder Cancer

completed accrual two expansion cohorts of up to 15 patients each with Non-muscle-invasive bladder cancer (NMIBC) or Non-metastatic muscle-invasive bladder cancer (MIBC) will be accrued at the highest dose

white blood cell count
atezolizumab
metastasis
renal function
bacillus calmette-guerin
  • 8 views
  • 24 Jan, 2021
  • 3 locations
A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

locally-advanced and metastatic urothelial cancer, which means the cancer has spread to nearby tissues or to other areas of the body. Other parts of the study will look at muscle-invasive bladder cancer

bcg vaccine
metastatic cancer
gemcitabine
metastasis
pembrolizumab
  • 284 views
  • 29 Apr, 2021
  • 82 locations
Relationship Between Methods of Bladder Tumor Extraction and Local Recurrence Rate

bladder cancer (NMIBC) (excluding carcinoma in-situ). However, more than half of patients will experience local recurrence after surgery. It is believed that one of the main causes for this local

  • 0 views
  • 05 Mar, 2021
  • 1 location
En-Bloc Resection of Bladder Tumors

potential to increase the rate of correct staging and accurate assignment of risk-classification in non-muscle-invasive bladder cancer (NMIBC) and to avoid re-TURBT in a considerable number of high-grade

  • 0 views
  • 18 Apr, 2021
  • 2 locations
Study of Genistein in Reducing Side Effects of Superficial Bladder Cancer Treatment

Patients with non-invasive bladder cancer are often treated with intravesical therapy in order to prevent the recurrence of bladder cancer. Intravesical therapy can cause many lower urinary

bladder tumor
invasive bladder cancer
bladder cancer
intravesical bcg
superficial bladder cancer
  • 9 views
  • 26 Jan, 2021
  • 3 locations
Durvalumab (MEDI4736) and TREmelimumab in NEOadjuvant Bladder Cancer Patients (DUTRENEO)

chemotherapy in patients with muscle-invasive bladder cancer (MIBC) Modest increase in overall survival, but only a subset of eligible patients are eligible to receive it. In addition, radical cystectomy

cystoscopy
durvalumab
carcinoma
gemcitabine
metastasis
  • 40 views
  • 26 Jan, 2021
  • 5 locations
Optimized Perioperative Antibiotic Prophylaxis in Radical Cystectomy

Cystectomy with urinary diversion (ileal conduit, orthotopic ileal bladder substitute, continent catheterizable pouch) is the best treatment option for patients with muscle-invasive bladder

invasive bladder cancer
postoperative complication
antibiotic prophylaxis
colitis
antibiotic therapy
  • 1 views
  • 24 Jan, 2021
  • 2 locations
Comparison of Safety and Efficacy of Detaenial Sigmoid Neobladder and Ileal Neobladder

Bladder cancer is a common malignant tumor of the urinary system, radical resection plus urinary diversion is the first choice of treatment for muscle invasive bladder cancer. Urinary diversion

bladder carcinoma
invasive bladder cancer
intravesical chemotherapy
recurrent bladder cancer
carcinoma
  • 0 views
  • 24 Jan, 2021
  • 1 location