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Found 111 clinical trials
Urine-based Detection of Non-muscle Invasive Bladder

Non-muscle invasive bladder cancer (NMIBC), which comprises approximately 75% of bladder tumors, has the highest recurrence rate of all cancers, with around 70% of the patients developing local

cystoscopy
bladder tumor
invasive bladder cancer
cancer
bladder cancer
  • 0 views
  • 24 Jan, 2021
  • 1 location
  • 95 views
  • 05 Mar, 2021
  • 171 locations
A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Gu rin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)

bladder cancer (NMIBC) who harbor fibroblast growth factor receptor (FGFR) mutations or fusions, and who recurred after bacillus calmette-guerin (BCG) therapy.

growth factor
bladder tumor
human chorionic gonadotropin
cancer
intravesical chemotherapy
  • 0 views
  • 02 Feb, 2021
  • 179 locations
Impact of Remimazolam on Prognosis After Bladder Cancer Surgery

Bladder cancer is one of the most common genitourinary cancers. Transurethral resection of bladder tumor (TURBT) is the standard therapy for nonmuscle invasive bladder cancer. However, patients

  • 0 views
  • 15 Feb, 2021
  • 1 location
A Study of TAR-200 in Combination With Cetrelimab TAR-200 Alone or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

The purpose of this study is to evaluate the overall complete response (CR) rate in participants treated with TAR-200 in combination with cetrelimab (Cohort 1), or TAR-200 alone (Cohort 2), or cetrelimab alone (Cohort 3) with Carcinoma in Situ (CIS), with or without concomitant high-grade Ta or T1 papillary disease.

  • 0 views
  • 05 Mar, 2021
  • 174 locations
Celecoxib With Chemotherapy in Localized Muscle-Invasive Bladder Cancer

The purpose of this study is to compare patient tumor tissue before and after treatment with chemotherapy plus celecoxib. Investigators will look at gene expression, to see what effect celecoxib may have on tumor cells.

metastasis
x-rays
tumor cells
bladder cancer
bladder carcinoma
  • 10 views
  • 25 Jan, 2021
  • 2 locations
Avelumab and Radiation in Muscle-Invasive Bladder Cancer

This research study is studying the effects of adding a certain type of immunotherapy to standard bladder-directed radiation as a treatment for muscle-invasive urothelial carcinoma of the bladder. The drug in this study is: Avelumab (also known as BAVENCIO)

bladder tumor
invasive bladder cancer
cancer
bladder carcinoma
bladder cancer
  • 0 views
  • 03 Mar, 2021
  • 2 locations
Pembrolizumab With Chemoradiotherapy as Treatment for Muscle Invasive Bladder Cancer

This study will enrol patients with maximally resected (via transurethral resection (TURBT) non-metastatic muscle invasive bladder cancer, who either wish to attempt bladder preservation therapy

conjugated bilirubin
pembrolizumab
bladder cancer
bladder carcinoma
carcinoma
  • 39 views
  • 30 Jan, 2021
  • 8 locations
Efficacy of Durvalumab in Non-muscle-invasive Bladder Cancer

Research Hypothesis Approximately 75% of patients with bladder cancer (BC) present with a disease confined to the mucosa (stage Ta, CIS) or submucosa (stage T1) (non-muscle invasive BC [NMIBC]). For high grade NMIBC, i.e. TaG3, T1G3 and CIS, intravesical bacillus Calmette-Gurin (BCG) immunotherapy is the treatment of choice, given that …

durvalumab
combinations
bladder tumor
invasive bladder cancer
cancer
  • 14 views
  • 26 Jan, 2021
  • 1 location
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy

This research study is studying a positron emission tomography (PET) agent called 18F-fluciclovine to evaluate how well 18F-fluciclovine-PET scans determine the extent of muscle invasive bladder

metastasis
invasive bladder cancer
bladder tumor
cancer
radiopharmaceuticals
  • 1 views
  • 23 Jan, 2021
  • 1 location