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Found 129 clinical trials
Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable

This is a phase II study to determine the safety and efficacy of tislelizumab when given in combination with nab-paclitaxel as treatment for patients with high-risk non-muscle-invasive bladder

  • 1 views
  • 06 Nov, 2021
  • 1 location
LUMINOS-103: A Basket Trial Evaluating the Safety and Efficacy of Lerapolturev (PVSRIPO) and Lerapolturev in Combination With Anti-PD-1/L1 Checkpoint Inhibitors in Patients With Advanced Solid Tumors

L1) monoclonal antibody (mAb) (which will be referred to throughout this protocol as "anti-PD-1/L1 therapy") therapy in adult patients with solid tumor cancers. Non-muscle invasive Bladder Cancer has

invasive bladder cancer
squamous cell carcinoma
measurable disease
carcinoma
immunomodulator
  • 0 views
  • 04 Oct, 2022
  • 1 location
Relationship Between Lymph Node Dissection and Prognosis in High-risk NMIBC

There is no consensus on the need for lymph node dissection in radical cystectomy (RC) for high-risk non-muscular invasive bladder cancer (NMIBC). Investigators divided participants at high risk

invasive bladder cancer
radical cystectomy
neutrophil count
transurethral resection
transurethral bladder excision
  • 0 views
  • 24 Nov, 2021
  • 1 location
Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC

Current treatment of localized muscle-invasive bladder cancer is still associated with high relapse and death rate as well as the need for complete bladder resection or irradiation. The

invasive bladder cancer
gemcitabine
atezolizumab
intravesical bcg
radical cystectomy
  • 0 views
  • 04 Oct, 2022
  • 9 locations
3 Ultrasound Guided Plane Blocks for Perioperative Analgesia in Patients Undergoing Radical Cystectomy

Radical cystectomy is the gold standard treatment for muscle invasive bladder cancer as well as some T1 and non-invasive disease. It is a major operation with significant perioperative morbidity

invasive bladder cancer
analgesia
opioid
regional anesthesia
bupivacaine
  • 0 views
  • 26 Apr, 2022
  • 1 location
Comparison of Safety and Efficacy of Detaenial Sigmoid Neobladder and Ileal Neobladder

Bladder cancer is a common malignant tumor of the urinary system, radical resection plus urinary diversion is the first choice of treatment for muscle invasive bladder cancer. Urinary diversion

invasive bladder cancer
recurrent bladder cancer
bladder carcinoma
hydronephrosis
urinary diversion
  • 0 views
  • 04 Oct, 2022
  • 1 location
Bladder Tumor Biopsy Study to Improve Preoperative Determination of Stage and Grade

To assess whether the addition of a bladder tumor biopsy improves the level of agreement between the pretreatment endoscopic impression and the final postoperative pathology determination of stage and grade in non-muscle-invasive urothelial carcinoma of the bladder.

transitional cell carcinoma
carcinoma
bladder tumor
bladder carcinoma
  • 0 views
  • 24 Mar, 2022
  • 1 location
Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy (FMBRT)

The purpose of this study is to examine the usefulness of implanting small 24-K gold fiducial markers around a bladder tumor site, so that a Radiation Oncologist can identify the original tumor location at the time of radiation treatment. Other goals of the study include assessing whether a new MRI …

renal function
primary cancer
bladder carcinoma
TURB
bladder tumor
  • 0 views
  • 14 Oct, 2022
  • 3 locations
Transurethral Modified En Bloc Resection For Large Bladder Tumours.

Modified en bloc resection is a hybrid technique involving piecemeal resection of the exophytic part of the bladder tumour, followed by en bloc resection of the tumour base. In this study, we shall investigate the efficacy of modified en bloc resection for patients with bladder tumours of ≥3cm in size.

  • 0 views
  • 15 Jul, 2022
  • 1 location
Multi-parameter Magnetic Resonance Imaging Guides Precise Treatment of Urothelial Carcinoma

PurposeTo evaluate whether immediate multiparametric MRI evaluate the sensitivity of modified neoadjuvant chemotherapy early in patient with muscle invasive bladder cancerMIBC. RationaleMultiparametric MRI may help detect the early changes of bladder cancer receiving neoadjuvant chemotherapy.

recurrent bladder cancer
invasive bladder cancer
gemcitabine
transurethral bladder excision
radical cystectomy
  • 0 views
  • 26 Jan, 2021
  • 1 location