Found 130 clinical trials
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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Family Medicine
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Currently Recruiting
A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer
Triple-Negative Invasive Breast Cancer
- 66 views
- 03 Dec, 2020
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Currently Recruiting
NSABP B-47: A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative Her2-Low Invasive Breast Cancer
by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative Her2-Low Invasive Breast Cancer
- 228 views
- 08 Nov, 2020
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Currently Recruiting
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer
n the present study the neoadjuvant approach with the anti-HER2 trastuzumab and pertuzumab combined with carboplatin and paclitaxel will be used to compare the Event-Free Survival (EFS) in regimens with and without atezolizumab. Following the neoadjuvant part of the study, after surgery all patients will continue to receive trastuzumab and …
- 17 views
- 12 Aug, 2019
- 35 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For females only
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Currently Recruiting
Axillary Node Dissection Versus no Dissection in Breast Cancer With Positive Sentinel Lymph Node
investigator propose a Non Inferiority Randomized Multicenter Phase III Trial of Axillary Node Dissection Versus no Axillary Node Dissection in Case of Positive Sentinel Lymph Node in Invasive Breast Cancer
- 0 views
- 26 Jan, 2020
- 1 location
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Multi-country trial
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Unknown Phase
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Currently Recruiting
RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy BREVITY
The current study (BREVITY) aims to provide validation results of RNA Disruption Assay (RDA) as a tumour response assessment tool that uses tumour core biopsies taken starting from 35 +/- 4 days after the initiation of neoadjuvant chemotherapy.
- 28 views
- 26 Jul, 2020
- 32 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Family Medicine
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Currently Recruiting
Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ
Although the results obtained from ECOG E5194 cohort 1 (criteria: mammographically detected low- or intermediate-grade DCIS, measuring less than 2.5 cm with margins 3 mm) and RTOG 9804 trial (the same enrolled clinicopathological features to cohort 1 of ECOG E5194 trial) demonstrated that the 7-year ipsilateral breast tumor recurrence (IBTR) …
- 9 views
- 12 Aug, 2019
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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millions of participants
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An interventional trial
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For females only
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Family Medicine
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Currently Recruiting
Prospective Trial of Digital Breast Tomosynthesis (DBT) in Breast Cancer Screening.
The accuracy of standard two dimension digital mammography (2DDM) in breast cancer screening is limited because of superimposition of normal breast structures onto a two dimensional image. Mammography signs of breast cancer may be obscured, resulting in delay in the diagnosis of breast cancer. Conversely, superimposition of normal tissues may …
- 1 views
- 11 Nov, 2019
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer
breast cancer. The hypothesis is that FFNP SUVmax from PET/MRI will correlate well against the semi-quantitative PR immunohistochemistry score.
- 0 views
- 20 Dec, 2020
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
A "Window Trial" on Curcumin for Invasive Breast Cancer Primary Tumors
The purpose of this study is to determine whether oral administration of curcumin causes biological changes in primary tumors of breast cancer patients.
- 0 views
- 25 Feb, 2020
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Stereotactic Body Radiation Therapy (SBRT) for Invasive Breast Cancer Patients Not Undergoing Definitive Surgery
This is a prospective pilot study investigating the safety and efficacy of stereotactic body radiation therapy (SBRT) as a treatment for breast cancer in patients who do not get surgery. The study will accrue 15 patients who will be treated to a dose of 40 Gy over the course of …
- 0 views
- 06 Sep, 2020
- 1 location