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Found 130 clinical trials
featured
  • 66 views
  • 03 Dec, 2020
  • 1 location
featured
  • 228 views
  • 08 Nov, 2020
  • 1 location
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer

n the present study the neoadjuvant approach with the anti-HER2 trastuzumab and pertuzumab combined with carboplatin and paclitaxel will be used to compare the Event-Free Survival (EFS) in regimens with and without atezolizumab. Following the neoadjuvant part of the study, after surgery all patients will continue to receive trastuzumab and …

tubal ligation
HER2
estrogen
sentinel node
residual tumor
  • 17 views
  • 12 Aug, 2019
  • 35 locations
Axillary Node Dissection Versus no Dissection in Breast Cancer With Positive Sentinel Lymph Node

investigator propose a Non Inferiority Randomized Multicenter Phase III Trial of Axillary Node Dissection Versus no Axillary Node Dissection in Case of Positive Sentinel Lymph Node in Invasive Breast Cancer

tumor cells
hormone therapy
metastasis
endocrine therapy
sentinel node
  • 0 views
  • 26 Jan, 2020
  • 1 location
RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy BREVITY

The current study (BREVITY) aims to provide validation results of RNA Disruption Assay (RDA) as a tumour response assessment tool that uses tumour core biopsies taken starting from 35 +/- 4 days after the initiation of neoadjuvant chemotherapy.

breast cancer
invasive breast cancer
cancer
adjuvant therapy
  • 28 views
  • 26 Jul, 2020
  • 32 locations
Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

Although the results obtained from ECOG E5194 cohort 1 (criteria: mammographically detected low- or intermediate-grade DCIS, measuring less than 2.5 cm with margins 3 mm) and RTOG 9804 trial (the same enrolled clinicopathological features to cohort 1 of ECOG E5194 trial) demonstrated that the 7-year ipsilateral breast tumor recurrence (IBTR) …

mammogram
breast cancer
breast tumor
estrogen receptor
cancer
  • 9 views
  • 12 Aug, 2019
  • 1 location
Prospective Trial of Digital Breast Tomosynthesis (DBT) in Breast Cancer Screening.

The accuracy of standard two dimension digital mammography (2DDM) in breast cancer screening is limited because of superimposition of normal breast structures onto a two dimensional image. Mammography signs of breast cancer may be obscured, resulting in delay in the diagnosis of breast cancer. Conversely, superimposition of normal tissues may …

mammogram
  • 1 views
  • 11 Nov, 2019
FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer

breast cancer. The hypothesis is that FFNP SUVmax from PET/MRI will correlate well against the semi-quantitative PR immunohistochemistry score.

progesterone receptor
immunohistochemistry
progesterone
  • 0 views
  • 20 Dec, 2020
  • 1 location
A "Window Trial" on Curcumin for Invasive Breast Cancer Primary Tumors

The purpose of this study is to determine whether oral administration of curcumin causes biological changes in primary tumors of breast cancer patients.

primary tumor
invasive breast cancer
estrogen
mammogram
  • 0 views
  • 25 Feb, 2020
  • 1 location
Stereotactic Body Radiation Therapy (SBRT) for Invasive Breast Cancer Patients Not Undergoing Definitive Surgery

This is a prospective pilot study investigating the safety and efficacy of stereotactic body radiation therapy (SBRT) as a treatment for breast cancer in patients who do not get surgery. The study will accrue 15 patients who will be treated to a dose of 40 Gy over the course of …

invasive breast cancer
invasive carcinoma
carcinoma
  • 0 views
  • 06 Sep, 2020
  • 1 location