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Found 71 clinical trials
Combination of Anti-PD-1 Antibody and Chemotherapy for Unresectable Intrahepatic Cholangiocarcinoma

Cisplatin in patients who were advanced intrahepatic cholangiocarcinoma with no chance for primary surgery.

  • 2 views
  • 24 Jan, 2021
  • 1 location
Durvalumab in Combination With a CSF-1R Inhibitor (SNDX-6532) Following Chemo or Radio-Embolization for Patients With Intrahepatic Cholangiocarcinoma

The purposed of this research is to study the safety and clinical activity of the combination of durvalumab and a CSF-1R inhibitor (SNDX-6352) in people with Intrahepatic Cholangiocarcinoma.

  • 0 views
  • 12 Mar, 2022
  • 1 location
Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver Cancer (SIROCHO)

Treatment of intrahepatic cholangiocarcinoma (ICC) remains difficult. Many patients have unresectable tumors, and survival after resection was only slightly improved with the use of adjuvant

  • 0 views
  • 09 Jul, 2022
  • 2 locations
Surveys, Blood Testing, and Fibroscan in Screening for Liver Fibrosis and Liver Cirrhosis

This clinical trial studies the use of surveys, blood testing, and fibroscan in screening for liver fibrosis and liver cirrhosis in new or existing patients of the HOPE clinic seeking usual clinical care. Fibroscan is an imaging procedure of the liver which uses a probe like an ultrasound. Information gathered …

  • 0 views
  • 16 Jun, 2022
  • 1 location
Futibatinib in Patients With Specific FGFR Aberrations

with advanced, metastatic or locally-advanced solid tumors harboring FGFR1-4 rearrangements (excluding primary brain tumors and intrahepatic cholangiocarcinoma [iCCA]); patients with gastric or gastro

  • 1 views
  • 23 Jul, 2022
  • 57 locations
REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

This is a Phase 1/2, open-label, FIH study designed to evaluate the safety, tolerability, PK, PDy, and antineoplastic activity of RLY-4008, a potent and highly selective FGFR2 inhibitor, in patients with unresectable or metastatic CCA and other solid tumors. The study consists of 3 parts: a dose escalation (Part 1), …

advanced solid tumor
FGFR2
cholangiocarcinoma
solid tumor
antineoplastic
  • 5 views
  • 25 Jul, 2022
  • 41 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

) Intrahepatic cholangiocarcinoma (closed to accrual 03/20/2018) Extrahepatic cholangiocarcinoma and bile duct tumors (closed to accrual 03/20/2018) Sarcomatoid carcinoma of

ct scan
immunosuppressive agents
human immunodeficiency virus
other cancer
parathyroid
  • 6634 views
  • 10 Aug, 2022
  • 752 locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

ct scan
human immunodeficiency virus
other cancer
fgfr inhibitor
cancer
  • 6575 views
  • 08 Aug, 2022
  • 909 locations
Bortezomib in Intrahepatic Cholangiocellular Carcinoma

This study evaluates the efficacy and safety of second-line treatment of bortezomib in advanced intrahepatic cholangiocarcinoma patients.Half of participants will receive bortezomib while the

cholangiocarcinoma
cisplatin/gemcitabine
measurable disease
gemcitabine
solid tumors
  • 2 views
  • 25 Feb, 2022
  • 1 location
Treatment of Advanced Intrahepatic Cholangiocarcinoma (TAICC)

The purpose of this study is to evaluate the efficacy and safety of Levamisole Hcl in the treatment of patients with advanced intrahepatic cholangiocarcinoma.

anlotinib hydrochloride
cancer
g-csf
cholangiocarcinoma
  • 6 views
  • 06 Feb, 2022
  • 1 location