Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 80 clinical trials
Trial Comparing Different Stimulation Paradigms in Patients Treated With Vagus Nerve Stimulation for Refractory Epilepsy

Patients with refractory epilepsy who are candidates for a treatment with vagus nerve stimulation will be prospectively randomized into 3 arms with different vagus nerve stimulation

intractable epilepsy
vagus nerve stimulation
seizure
antiepileptics
  • 9 views
  • 07 Nov, 2020
  • 1 location
Emotional Processing and Memory Evaluation in Epilepsy Patients

or left temporal lobectomy for the treatment of medically intractable epilepsy. It is expected participants with known lateralized dysfunction will exhibit differential ability to

temporal lobe epilepsy
intractable epilepsy
seizure
  • 112 views
  • 07 Nov, 2020
  • 1 location
Hippocampal and Thalamic DBS for Bilateral Temporal Lobe Epilepsy

The study aims to compare the safety and effectiveness of deep brain stimulation of the hippocampus and the anterior nucleus of the thalamus for reducing the frequency of seizures in patients with bilateral temporal lobe epilepsy.

  • 1 views
  • 23 Jan, 2021
  • 1 location
Home Operations Utilizing Stimulation

This project will utilize a home-operated stimulator in 1) a healthy young adult population and 2) a healthy older adult population to provide a proof of concept of home-use of transcutaneous vagal nerve stimulation (tVNS). tVNS is believed to modulate cognitive performance.

  • 0 views
  • 29 Jan, 2021
  • 1 location
Efficacy of Modified Ketogenic Diet (Atkins) in Management of Epilepsy

The purpose of this study is to determine whether patients with uncontrolled epilepsy can follow a low carbohydrate diet long-term and if so, how will that diet affect their seizures

ketogenic diet
atkins diet
seizure
  • 52 views
  • 07 Nov, 2020
  • 1 location
Transcranial Direct Current Stimulation (tDCS) As A Tool For Prospective Responder Identification Before Vagus Nerve Stimulation (VNS) Implantation

The aim of the study is to establish tDCS as a prognostic tool to predict VNS therapy outcome among patients with pharmacoresistant epilepsy.

intractable epilepsy
antiepileptics
seizure
vagus nerve stimulation
epilepsy surgery
  • 14 views
  • 07 Nov, 2020
  • 1 location
A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy

The purpose of this study is to assess the safety and feasibility of Magnetic Resonance Imaging-guided focused ultrasound (MRgFUS) in patients with epilepsy whose medicines are not working well. The ExAblate transcranial system is the name of the device that will be used to create and send ultrasound waves through …

  • 25 views
  • 25 Jan, 2021
  • 1 location
Effects of Keppra on Thinking Emotions and Balance in Elderly Healthy Volunteers

Epilepsy is a common disorder with an incidence of about 6 per 1000. The incidence progressively increases above age 50. By age 75, the incidence is two to three fold compared with any age group. Unfortunately, older individuals are especially at risk to incur significant side effects to anti-epileptic drugs. …

antiepileptics
anti-epileptic drug
seizure
levetiracetam
keppra
  • 4108 views
  • 07 Nov, 2020
  • 1 location
Tele-epic (Telemedicine for Epilepsy Care)

Epilepsy is a chronic condition that requires consistent follow-up aimed at seizure control, surveillance of comorbidities, monitoring of antiepileptic drugs (AED) levels and side effects. Patients may encounter difficulties to be assessed adequately and the disease burden is increased by the need for travelling across the country for medical consultations. …

epilepsy
antiepileptics
seizure
antiepileptic
  • 0 views
  • 25 Jan, 2021
  • 1 location
Long-term Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex

The primary objective of clinical part of EPISTOP project is to identify the clinical and molecular biomarkers of epileptogenesis in a prospective clinical study of patients with TSC. Secondary objective of the clinical part of EPISTOP is to compare the effects of standard antiepileptic treatment in patients diagnosed as having …

epilepsy
antiepileptics
seizure
antiepileptic
  • 4 views
  • 08 Nov, 2020
  • 1 location