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Found 55 clinical trials
Multisession Radiosurgery in Residual/Recurrent Grade II Meningiomas.

Fractionated radiosurgery will be delivered to atypical meningioma lesions in salvage setting for patients who present post-surgical residual lesion or develop recurrence.

  • 0 views
  • 24 Oct, 2021
  • 1 location
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed

tumor cells
intracranial meningioma
step 2
ct scan
central pathology review
  • 1015 views
  • 21 Mar, 2022
  • 131 locations
The Safety of Intravenous Tranexamic Acid in Patients Undergoing Supratentorial Meningiomas Resection

problem of concern, especially in neurosurgery. Therefore, this study aims to provide a scientific evidence for the safety of TXA in supratentorial meningiomas resection patients.

tranexamic acid
  • 0 views
  • 29 Oct, 2021
  • 1 location
Sunitinib in Treating Patients With Recurrent or Unresectable Meningioma Intracranial Hemangiopericytoma or Intracranial Hemangioblastoma

works in treating patients with recurrent or unresectable meningioma, intracranial hemangiopericytoma, or intracranial hemangioblastoma.

  • 89 views
  • 07 Nov, 2020
  • 2 locations
Apatinib in the Treatment of Recurrent Atypical/Malignant Meningioma in Adults

Apatinib mesylate may be an effective treatment for recurrent atypical/malignant meningioma. This prospective clinical study is now planned to verify the effectiveness and safety of apatinib

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location
Carbon Ion Radiotherapy for Atypical Meningiomas (MARCIE)

Treatment standard for patients with atypical or anaplastic meningioma is neurosurgical resection. With this approach, local control ranges between 50 and 70%, depending on resection status. A

malignant meningioma
atypical meningioma
  • 42 views
  • 03 Mar, 2022
  • 1 location
Exploratory Study of PD-1 Neoadjuvant Treatment of Recurrent Meningioma

This research study is studying a drug as a possible treatment for High Grade Meningioma.

dexamethasone
recurrent meningioma
tumor cells
  • 0 views
  • 19 Aug, 2021
  • 1 location
Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma

The purpose of this research study is to determine the effects bevacizumab (the study drug) combined with Optune (the study device) tumor treatment field therapy has on meningiomas. Bevacizumab

blood transfusion
brain tumor
unresectable meningioma
hysterectomy
growth factors
  • 1 views
  • 08 Jun, 2022
  • 6 locations
Neoadjuvant Avelumab and Hypofractionated Proton Radiation Therapy Followed by Surgery for Recurrent Radiation-refractory Meningioma

tumors or prior radiation therapy, and a recent case study reported significant reduction of an intracranial meningioma after 6 months of PD-L1 blockade. Radiation has been shown to augment immune

dexamethasone
blood transfusion
medical therapy
proton therapy
karnofsky performance status
  • 108 views
  • 04 Mar, 2022
  • 1 location
Combination of Alpelisib and Trametinib in Progressive Refractory Meningiomas

-III meningiomas progression-free survival (PFS) 6 is at 10-15%. Median PFS grade III meningioma is approximate 3 years. Alpelisib is a well-tolerated Phosphoinositide 3-kinase (Pi3K) specific

renal function
mekinist
grade iii meningioma
  • 50 views
  • 25 Jan, 2021
  • 1 location