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Found 15 clinical trials
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Efficacy of Neoadjuvant Therapy With Cisplatin Plus Mitomycin C in BRCA1-Mutated Ovarian Cancer

This study was designed to assess the safety and efficacy of neoadjuvant therapy with mitomycin C plus cisplatin (MP) in BRCA1-mutated ovarian cancer versus standard regimen (paclitaxel plus carboplatin (TP)).

  • 0 views
  • 18 Feb, 2021
  • 1 location
None
Aspirin for Prevention of Venous Thromboembolism Among Ovarian Cancer Patients Receiving Neoadjuvant Chemotherapy

This is a pilot study to determine the safety and efficacy of low dose aspirin for the prevention of venous thromboembolism among women with advanced ovarian cancer receiving neoadjuvant chemotherapy.

cancer
ovarian epithelial carcinoma
ovarian epithelial cancer
venous thromboembolism
angiogenesis inhibitor
  • 0 views
  • 16 Aug, 2021
  • 2 locations
None
Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients

This study tests the hypothesis that IV iron sucrose infusions given to iron deficient ovarian cancer patients prior to debulking surgery can improve pre-operative iron stores and decrease transfusion of packed red blood cells in the peri-operative period. 21 participants at least 18 years of age with epithelial ovarian cancer …

anemia
cancer
debulking surgery
iron sucrose
iron
  • 5 views
  • 27 Jan, 2021
  • 1 location
None
Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian Fallopian Tube or Primary Peritoneal Cancer

The proposed study design is a single arm Phase II trial to document the feasibility of carboplatin-mirvetuximab - in patients with advanced-stage EOC. Patients with biopsy confirmed, newly diagnosed, advanced-stage serous EOC deemed appropriate for NACT will have their tumors evaluated for FR receptor over-expression via a centralized immunohistochemical assay …

cytoreductive surgery
ovarian epithelial carcinoma
cytotoxic chemotherapy
cancer of the ovary
mirvetuximab soravtansine
  • 0 views
  • 19 Jul, 2021
  • 1 location
None
Translational Analysis In Longitudinal Series of Ovarian Cancer ORganoids

)+adjuvant chemotherapy and neoadjuvant chemotherapy + interval debulking surgery (NACT+IDS) cases as model for the patients' response to treatments. Since organoids represent a model system comparable to

  • 0 views
  • 25 Jan, 2021
  • 1 location